Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20922186 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHTTTSHRHSD17B1 | |
| SCHEMBL16134063 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAHTTTSHRHSD17B1 | |
| SCHEMBL16134069 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAHTTTSHRHSD17B1 | |
| SCHEMBL359701 | 0.79 | MAPT (0.56) | SMN1; SMN2LMNAHTTTSHRHSD17B1 | |
| SCHEMBL29098689 | 0.79 | HPGD (0.61) | SMN1; SMN2LMNAHTTTSHRHSD17B1 | |
| SCHEMBL11362638 | 0.78 | ALDH1A1 (0.60) | SMN1; SMN2LMNATSHRALDH1A1KDM4E | |
| SCHEMBL3914119 | 0.77 | LMNA (0.56) | SMN1; SMN2LMNATSHRALDH1A1KDM4E | |
| SCHEMBL28485570 | 0.77 | LMNA (0.56) | SMN1; SMN2LMNAHTTTSHRALDH1A1 | |
| SCHEMBL9837774 | 0.77 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAHTTHSD17B1HSD17B2 | |
| SCHEMBL374670 | 0.77 | HSD17B1 (0.48) | SMN1; SMN2LMNAHTTTSHRHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032524-A1 | COUPLING COMPOUNDS AND HAIR DYEING COMPOSITIONS CONTAINING THEM | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007118818-A1 | COUPLING COMPOUNDS AND HAIR DYEING COMPOSITIONS CONTAINING THEM | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 2007-10-25 | — | — | WO | disclosed |
| EP-1847526-A1 | Coupling compounds and hair dyeing compositions containg them | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2007-10-24 | — | — | EP | disclosed |