Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30837754 | 1.00 | TSHR (0.67) | TSHRGAAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3276214 | 0.86 | ALDH1A1 (0.57) | TSHRGAAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2907446 | 0.86 | HTT (0.60) | TSHRGAAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6165389 | 0.84 | TDP1 (0.64) | TSHRGAAHTTSMN1; SMN2MAPT | |
| SCHEMBL2351986 | 0.81 | TSHR (0.47) | TSHRGAAHTTSMN1; SMN2ALDH1A1 | |
| 2,4-Dichlorophenoxyacetic Acid, Methyl Ester SCHEMBL5004223 | 0.80 | MAPT (0.70) | TSHRGAAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7359407 | 0.78 | PTGDR (0.55) | TSHRGAAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL19311844 | 0.78 | TSHR (0.68) | TSHRGAAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4899476 | 0.78 | LMNA (0.64) | TSHRGAAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3273629 | 0.78 | LMNA (0.64) | TSHRGAAHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10624903-B2 | Longer-acting progestin prodrug contraceptives | EVESTRA, INC. (US) | 2020-04-21 | — | — | US | disclosed |
| WO-2019078983-A1 | LONGER-ACTING PROGESTIN PRODRUG CONTRACEPTIVES | EVESTRA, INC. (US) | 2019-04-25 | — | — | WO | disclosed |
| US-20190117670-A1 | LONGER-ACTING PROGESTIN PRODRUG CONTRACEPTIVES | EVESTRA, INC. | 2019-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190117670-A1 | LONGER-ACTING PROGESTIN PRODRUG CONTRACEPTIVES | CYP19A1, PGR, GNRHR | TSHR 494/4885GAA 3393/4885HTT 3084/4885 |
| US-10624903-B2 | Longer-acting progestin prodrug contraceptives | CYP19A1, PGR, GNRHR | TSHR 494/4885GAA 3393/4885HTT 3084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.