Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 4/20 | 0.32 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | G6PD | P11413 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17758752 | 0.83 | NOTUM (0.39) | NOTUMF2RL1RORCLMNAKDM4E | |
| SCHEMBL23352228 | 0.83 | NOTUM (0.36) | NOTUMMETF2RL1LMNAKDM4E | |
| SCHEMBL17758753 | 0.82 | NOTUM (0.49) | POLBNOTUMF2RL1RORCKDM4E | |
| SCHEMBL20929259 | 0.78 | POLB (0.35) | POLBNOTUMMETUSP1LMNA | |
| SCHEMBL17758865 | 0.78 | IDH1 (0.38) | POLBNOTUMMETUSP1LMNA | |
| SCHEMBL14961826 | 0.75 | POLB (0.47) | POLBNOTUMLMNAKDM4EALDH1A1 | |
| SCHEMBL23352193 | 0.75 | LMNA (0.45) | NOTUMF2RL1LMNAKDM4EALDH1A1 | |
| SCHEMBL23352236 | 0.73 | USP9X (0.45) | F2RL1RORCLMNAKDM4EALDH1A1 | |
| SCHEMBL23352192 | 0.73 | USP9X (0.41) | F2RL1RORCKDM4EALDH1A1MEN1 | |
| SCHEMBL17758802 | 0.73 | LMNA (0.39) | NOTUMMETLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019079519-A1 | BROAD SPECTRUM ANTIVIRAL COMPOSITIONS AND METHODS | FORGE LIFE SCIENCE, LLC (US) | 2019-04-25 | — | — | WO | disclosed |