Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17758865 | 0.85 | IDH1 (0.38) | LMNANOTUMIDH1NPBWR1MCHR1 | |
| SCHEMBL17758752 | 0.84 | NOTUM (0.39) | LMNANOTUMIDH1PI4KBGRIN1 | |
| SCHEMBL20929258 | 0.73 | POLB (0.36) | LMNANOTUMMETMAPTKDM4E | |
| SCHEMBL21695587 | 0.73 | LMNA (0.36) | LMNARAB9AHCRTR1HCRTR2MAPT | |
| SCHEMBL17758753 | 0.72 | NOTUM (0.49) | NOTUMKDM4EALDH1A1MAPK1 | |
| SCHEMBL23352228 | 0.72 | NOTUM (0.36) | LMNANOTUMMETMAPTKDM4E | |
| SCHEMBL21695609 | 0.72 | PDGFRB (0.35) | LMNARAB9AGRIN1GRIN2BMAPT | |
| SCHEMBL21695586 | 0.71 | MLYCD (0.34) | LMNARAB9AMAPTSYKALDH1A1 | |
| SCHEMBL23352192 | 0.70 | USP9X (0.41) | NPBWR1HCRTR1HCRTR2MAPTKDM4E | |
| SCHEMBL23352236 | 0.70 | USP9X (0.45) | LMNANPBWR1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11358961-B2 | Anti-HCMV compositions and methods | EVRYS BIO, LLC (US) | 2022-06-14 | — | — | US | disclosed |
| US-20220135556-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | EVRYS BIO, LLC (US) | 2022-05-05 | — | — | US | disclosed |
| EP-3218373-B1 | ANTI-HCMV COMPOSITIONS AND METHODS | EVRYS BIO LLC (US) | 2020-07-22 | — | — | EP | disclosed |
| US-20200140429-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | EVRYS BIO, LLC (US) | 2020-05-07 | — | — | US | disclosed |
| US-10556894-B2 | Anti-HCMV compositions and methods | EVRYS BIO, LLC (US) | 2020-02-11 | — | — | US | disclosed |
| WO-2016077232-A2 | ANTI-HCMV COMPOSITIONS AND METHODS | FORGE LIFE SCIENCE, LLC (US) | 2016-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11358961-B2 | Anti-HCMV compositions and methods | RPL35, RPL7, RPL5 | LMNA 1720/4885RAB9A 3866/4885NOTUM 3271/4885 |
| US-10556894-B2 | Anti-HCMV compositions and methods | RPL35, RPL7, RPL5 | LMNA 1720/4885RAB9A 3866/4885NOTUM 3271/4885 |
| US-20200140429-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | RPL35, RPL7, RPL5 | LMNA 1720/4885RAB9A 3866/4885NOTUM 3271/4885 |
| US-20220135556-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | RPL35, RPL7, RPL5 | LMNA 1720/4885RAB9A 3866/4885NOTUM 3271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.