Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | USP9X | Q93008 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17758865 | 0.87 | IDH1 (0.38) | NOTUMLMNAERCC1ERCC4IDH1 | |
| SCHEMBL17758753 | 0.86 | NOTUM (0.49) | NOTUMF2RL1MAPK1KDM4EALDH1A1 | |
| SCHEMBL23352228 | 0.85 | NOTUM (0.36) | NOTUMLMNAF2RL1MAPK1KDM4E | |
| SCHEMBL17758802 | 0.84 | LMNA (0.39) | NOTUMLMNAERCC1ERCC4IDH1 | |
| SCHEMBL20929258 | 0.83 | POLB (0.36) | NOTUMLMNAF2RL1MAPK1KDM4E | |
| SCHEMBL23352193 | 0.79 | LMNA (0.45) | NOTUMLMNAF2RL1KDM4EALDH1A1 | |
| SCHEMBL23352192 | 0.78 | USP9X (0.41) | F2RL1USP9XKDM4EALDH1A1RORC | |
| SCHEMBL23352236 | 0.78 | USP9X (0.45) | LMNAF2RL1USP9XKDM4EALDH1A1 | |
| SCHEMBL23352222 | 0.77 | NOTUM (0.38) | NOTUMLMNAF2RL1ERCC1ERCC4 | |
| SCHEMBL20929546 | 0.73 | SLC6A3 (0.36) | LMNAGLSKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459321-B2 | Broad spectrum antiviral compositions and methods | EVRYS BIO, LLC (US) | 2022-10-04 | — | — | US | disclosed |
| US-11358961-B2 | Anti-HCMV compositions and methods | EVRYS BIO, LLC (US) | 2022-06-14 | — | — | US | disclosed |
| US-20220135556-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | EVRYS BIO, LLC (US) | 2022-05-05 | — | — | US | disclosed |
| US-20210139475-A1 | Broad Spectrum Antiviral Compositions and Methods | EVRYS BIO, LLC (US) | 2021-05-13 | — | — | US | disclosed |
| EP-3218373-B1 | ANTI-HCMV COMPOSITIONS AND METHODS | EVRYS BIO LLC (US) | 2020-07-22 | — | — | EP | disclosed |
| US-20200140429-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | EVRYS BIO, LLC (US) | 2020-05-07 | — | — | US | disclosed |
| US-10556894-B2 | Anti-HCMV compositions and methods | EVRYS BIO, LLC (US) | 2020-02-11 | — | — | US | disclosed |
| WO-2016077232-A2 | ANTI-HCMV COMPOSITIONS AND METHODS | FORGE LIFE SCIENCE, LLC (US) | 2016-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11459321-B2 | Broad spectrum antiviral compositions and methods | IRF3, MAVS, ZC3HAV1 | NOTUM 3929/4885LMNA 2718/4885F2RL1 4717/4885 |
| US-11358961-B2 | Anti-HCMV compositions and methods | RPL35, RPL7, RPL5 | NOTUM 3271/4885LMNA 1720/4885F2RL1 4715/4885 |
| US-10556894-B2 | Anti-HCMV compositions and methods | RPL35, RPL7, RPL5 | NOTUM 3271/4885LMNA 1720/4885F2RL1 4715/4885 |
| US-20210139475-A1 | Broad Spectrum Antiviral Compositions and Methods | MAVS, IRF3, ZC3HAV1 | NOTUM 3824/4885LMNA 3185/4885F2RL1 4466/4885 |
| US-20200140429-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | RPL35, RPL7, RPL5 | NOTUM 3271/4885LMNA 1720/4885F2RL1 4715/4885 |
| US-20220135556-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | RPL35, RPL7, RPL5 | NOTUM 3271/4885LMNA 1720/4885F2RL1 4715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.