SCHEMBL2093333

SCHEMBL2093333

Cc1ccc(NC([O])=O)cc1

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.67
POLB P06746 2/20 0.64
NPC1 O15118 4/20 0.61
RAB9A P51151 3/20 0.61
KIF11 P52732 1/20 0.57
TGM2 P21980 1/20 0.57
KDM4E B2RXH2 1/20 0.57
MAPT P10636 3/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
NMT1 P30419 1/20 0.53
DDAH1 O94760 1/20 0.52
ALDH1A1 P00352 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11461040 0.87 SMN1; SMN2 (0.48) TDP1POLBNPC1RAB9AKDM4E
SCHEMBL1275920 0.82 ALDH1A1 (0.70) TDP1POLBNPC1RAB9AKDM4E
SCHEMBL455439 0.82 TDP1 (0.70) TDP1POLBNPC1RAB9AKIF11
SCHEMBL6850999 0.82 KDM4E (0.79) TDP1POLBNPC1RAB9AKIF11
SCHEMBL27177335 0.80 ALDH1A1 (0.46) TDP1POLBNPC1RAB9AKDM4E
Fluoride SCHEMBL11790965 0.80 TDP1 (0.67) TDP1POLBNPC1RAB9AKIF11
SCHEMBL61417 0.80 TDP1 (1.00) TDP1POLBNPC1RAB9AKDM4E
SCHEMBL81433 0.78 KIF11 (0.88) TDP1POLBNPC1RAB9AKIF11
SCHEMBL5932492 0.78 TDP1 (0.64) TDP1POLBNPC1RAB9AKIF11
SCHEMBL11790956 0.78 TDP1 (0.64) TDP1POLBNPC1RAB9AKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050096406-A1 Reactive diluents and alkyd resin coating compositions PRETOT ROGER (CH) 2005-05-05 US claimed
EP-1480940-A2 REACTIVE DILUENTS AND ALKYD RESIN COATING COMPOSITIONS Ciba SC Holding AG (CH) 2004-12-01 EP claimed
WO-2003074466-A2 REACTIVE DILUENTS AND ALKYD RESIN COATING COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO claimed
US-5238909-A For preemergence or postemergence use EASTMAN KODAK COMPANY (US) 1993-08-24 US claimed
EP-0476760-A2 4-substituted isoxazole herbicides EASTMAN KODAK COMPANY (US) 1992-03-25 EP claimed
US-4154577-A Uniformly disperse dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-05-15 US claimed
US-4150943-A Uniformly dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-04-24 US claimed
CN-118239868-A Carbamate substituted styryl sulfone compound and preparation method and application thereof 华夏生生药业(北京)有限公司 2024-06-25 CN disclosed
US-8163753-B2 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2012-04-24 US disclosed
EP-1678185-B1 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMA CO LTD (JP) 2008-10-08 EP disclosed
US-20080119478-A1 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis OTSUKA PHAMACEUTICAL CO., LTD. (JP) 2008-05-22 US disclosed
EP-1678185-A1 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-07-12 EP disclosed
US-20060088786-A1 Rewritable optical information recording medium, recording and reproducing methods, as well as recording and reproducing apparatus MITSUI CHEMICALS, INC. (JP) 2006-04-27 US disclosed
US-4191574-A AZO-METHINE DYES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-03-04 US disclosed
US-4157893-A MONO OR DISAZO DYE CONTAINING AN AMINO-SUBSTITUTED PYRIMIDINE RING BASF AKTIENGESELLSCHAFT (DE) 1979-06-12 US disclosed
US-4154577-A Uniformly disperse dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-05-15 US disclosed
US-4150943-A Uniformly dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-04-24 US disclosed
US-4146535-A Azo dyes having a 3-cyano- or 3-carbamoyl-2,6-diamino-pyridine coupling component BASF AKTIENGESELLSCHAFT (DE) 1979-03-27 US disclosed
US-4143166-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1979-03-06 US disclosed
US-4138264-A Silver halide emulsion containing two equivalent type coupler for use in photography KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060088786-A1 Rewritable optical information recording medium, recording and reproducing methods, as well as recording and reproducing apparatus ALPG, TRPC6, GNRHR TDP1 316/4885POLB 1763/4885NPC1 4636/4885
US-20080119478-A1 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis NR2C2, NR0B2, NR4A2 TDP1 4548/4885POLB 757/4885NPC1 3130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.