Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 13/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21138127 | 0.73 | CCNC (0.45) | IDO1SLC22A12 | |
| SCHEMBL1038019 | 0.70 | GAA (0.45) | IDO1SLC22A12 | |
| SCHEMBL24469567 | 0.67 | GAK (0.44) | IDO1SLC22A12 | |
| SCHEMBL20534712 | 0.67 | CES2 (0.44) | — | |
| SCHEMBL29878298 | 0.66 | PKM (0.54) | IDO1SLC22A12 | |
| SCHEMBL28659540 | 0.66 | PKM (0.54) | IDO1SLC22A12 | |
| SCHEMBL7372413 | 0.66 | LMNA (0.60) | SLC22A12 | |
| SCHEMBL27788468 | 0.66 | TBXA2R (0.51) | TBXA2R | |
| SCHEMBL20534476 | 0.66 | FFAR1 (0.44) | TBXA2R | |
| SCHEMBL27640849 | 0.65 | TSHR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019078968-A2 | CYCLIC COMPOUNDS AS IMMUNOMODULATING AGENTS | ANGEX PHARMACEUTICAL, INC. (US) | 2019-04-25 | — | — | WO | disclosed |