Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 13/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30276240 | 1.00 | MEN1 (0.57) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL6420807 | 0.90 | HTR6 (0.57) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL30558134 | 0.86 | NOD1 (0.53) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL14502515 | 0.86 | NOD1 (0.53) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL17927644 | 0.83 | HTR6 (0.41) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL30276218 | 0.81 | CA12 (0.52) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL369194 | 0.81 | CA12 (0.52) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL20853109 | 0.80 | PTGDR2 (0.42) | MEN1KMT2AHTR6CXCL8NOD1 | |
| SCHEMBL17433427 | 0.80 | LMNA (0.40) | MEN1KMT2AHTR6L3MBTL1CXCL8 | |
| SCHEMBL23971189 | 0.80 | NOD1 (0.38) | MEN1KMT2AHTR6POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111225915-B | Imidazopyridine compounds as PAD inhibitors | 朱比兰特埃皮帕德有限公司 | 2023-03-07 | — | — | CN | disclosed |
| EP-3697785-B1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | Jubilant Epipad LLC (US) | 2022-12-28 | — | — | EP | disclosed |
| EP-3697785-B1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | Jubilant Epipad LLC (US) | 2022-12-28 | — | — | EP | disclosed |
| US-11426412-B2 | Imidazo-pyridine compounds as PAD inhibitors | Jubilant Epipad LLC (US) | 2022-08-30 | — | — | US | disclosed |
| US-20200237771-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | Jubilant Epipad LLC | 2020-07-30 | — | — | US | disclosed |
| US-20200237771-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | Jubilant Epipad LLC | 2020-07-30 | — | — | US | disclosed |
| CN-111225915-A | Imidazopyridine compounds as PAD inhibitors | 朱比兰特埃皮帕德有限公司 | 2020-06-02 | — | — | CN | disclosed |
| WO-2019077631-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200237771-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | PADI4, PADI1, PADI2 | MEN1 1497/4885KMT2A 3130/4885HTR6 3562/4885 |
| US-11426412-B2 | Imidazo-pyridine compounds as PAD inhibitors | PADI4, PADI1, PADI2 | MEN1 1497/4885KMT2A 3130/4885HTR6 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.