Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2453125 | 0.75 | CDK4 (0.42) | L3MBTL1HTR6ALDH1A1LMNARAB9A | |
| SCHEMBL14613631 | 0.73 | CYP1A2 (0.47) | CYP1A2CYP2A6HTR7ACSS2HDAC8 | |
| SCHEMBL10289623 | 0.72 | HTR6 (0.57) | CYP1A2CYP2A6HTR7HDAC8HTR6 | |
| SCHEMBL9914897 | 0.70 | KEAP1 (0.42) | GAACYP3A4ALDH1A1MAPTALOX15 | |
| SCHEMBL8303438 | 0.70 | CYP2A6 (0.50) | CYP1A2CYP2A6HTR7L3MBTL1MAPT | |
| SCHEMBL11928529 | 0.68 | HTR6 (0.63) | HTR7HDAC8L3MBTL1CYP3A4HTR6 | |
| SCHEMBL22156293 | 0.66 | HTR7 (0.43) | CYP1A2CYP2A6HTR7HDAC8L3MBTL1 | |
| SCHEMBL14457826 | 0.65 | KMT2A (0.57) | HTR7HDAC8CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9001732 | 0.64 | NOTUM (0.54) | CYP1A2CYP2A6HTR7HDAC8TP53 | |
| SCHEMBL22185251 | 0.64 | PLA2G4A (0.48) | CYP1A2CYP2A6HDAC8TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019077631-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-04-25 | — | — | WO | disclosed |