Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.49 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | GAPDH | P04406 | 2/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | HRAS | P01112 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.40 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.40 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27094317 | 0.91 | GAPDH (0.46) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL20938335 | 0.84 | P2RX3 (0.55) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL20938425 | 0.84 | P2RX3 (0.54) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL7110607 | 0.82 | P2RX3 (0.53) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL6099599 | 0.81 | P2RX3 (0.55) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL6099608 | 0.81 | P2RX3 (0.55) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL20058777 | 0.79 | ADK (0.51) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL20141981 | 0.78 | HRAS (0.60) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL13169185 | 0.78 | P2RX3 (0.75) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL9189337 | 0.78 | P2RX3 (0.75) | P2RX3P2RX4P2RX2MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019076633-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF PARASITIC INFECTIONS | UNIVERSITEIT GENT (BE) | 2019-04-25 | — | — | WO | disclosed |