Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.54 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.54 |
| ▸ | ADK | P55263 | 10/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 2/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.45 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.43 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | HRAS | P01112 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20058777 | 0.92 | ADK (0.51) | P2RX3P2RX4P2RX2ADKMEN1 | |
| SCHEMBL20938335 | 0.90 | P2RX3 (0.55) | P2RX3P2RX4P2RX2ADKMEN1 | |
| SCHEMBL30050679 | 0.90 | ADK (0.52) | P2RX3P2RX4P2RX2ADKMEN1 | |
| SCHEMBL13021362 | 0.90 | ADK (0.52) | P2RX3P2RX4P2RX2ADKMEN1 | |
| SCHEMBL13410466 | 0.90 | ADK (0.52) | P2RX3P2RX4P2RX2ADKMEN1 | |
| SCHEMBL12374608 | 0.90 | ADK (0.52) | P2RX3P2RX4P2RX2ADKMEN1 | |
| SCHEMBL2787845 | 0.90 | ADK (0.52) | P2RX3P2RX4P2RX2ADKMEN1 | |
| SCHEMBL18595659 | 0.90 | ADK (0.52) | P2RX3P2RX4P2RX2ADKMEN1 | |
| SCHEMBL18595740 | 0.90 | ADK (0.52) | P2RX3P2RX4P2RX2ADKMEN1 | |
| SCHEMBL7110607 | 0.88 | P2RX3 (0.53) | P2RX3P2RX4P2RX2ADKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11072628-B2 | Nucleoside analogues for the treatment of parasitic infections | UNIVERSITEIT GENT (BE) | 2021-07-27 | — | — | US | disclosed |
| US-20210024566-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF PARASITIC INFECTIONS | UNIVERSITEIT GENT (BE) | 2021-01-28 | — | — | US | disclosed |
| WO-2019076633-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF PARASITIC INFECTIONS | UNIVERSITEIT GENT (BE) | 2019-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11072628-B2 | Nucleoside analogues for the treatment of parasitic infections | PNP, NUDT1, SAMHD1 | P2RX3 282/4885P2RX4 300/4885P2RX2 303/4885 |
| US-20210024566-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF PARASITIC INFECTIONS | PNP, NUDT1, SAMHD1 | P2RX3 282/4885P2RX4 300/4885P2RX2 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.