SCHEMBL209405

SCHEMBL209405

CCC(=C(CC)c1ccc(O)c(O)c1C)c1ccc(O)c(O)c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.37
ESR1 P03372 4/20 0.37
ESR2 Q92731 4/20 0.37
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 2/20 0.37
ALOX15 P16050 2/20 0.37
KMT2A Q03164 2/20 0.37
HSD17B10 Q99714 2/20 0.37
AR P10275 2/20 0.37
NR1I2 O75469 1/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
NR3C1 P04150 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
FYN P06241 1/20 0.37
PGR P06401 1/20 0.37
CHRM2 P08172 1/20 0.37
ADRB1 P08588 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7904832 0.79 HSP90AB1 (0.53) MAPTALDH1A1MEN1ALOX15KMT2A
SCHEMBL12672384 0.71 SELL (0.46) MAPTALDH1A1MEN1ALOX15KMT2A
SCHEMBL30589153 0.71 SELL (0.64) MAPTESR2ALDH1A1MEN1ALOX15
SCHEMBL38623 0.71 SELL (0.64) MAPTESR2ALDH1A1MEN1ALOX15
SCHEMBL31290749 0.70 TRPA1 (0.46) MAPTESR1ESR2ALDH1A1MEN1
SCHEMBL3708636 0.70 TRPA1 (0.46) MAPTESR1ESR2ALDH1A1MEN1
SCHEMBL23919938 0.70 AMY1A (0.47) MAPTESR1ESR2MEN1ALOX15
SCHEMBL29557387 0.69 ALDH1A1 (0.52) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL23067279 0.69 ALDH1A1 (0.52) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL9768251 0.69 MAPT (0.40) MAPTALDH1A1MEN1ALOX15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE43067-E1 Method for producing new polynuclear poly(formylphenol) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-01-03 US disclosed
US-7750190-B2 reacting hexamethylene tetramine in presence of acid; industrial scale; photoresists HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2010-07-06 US disclosed
US-20090182175-A1 METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090182175-A1 METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) PCBP1, FPR2, PNKP MAPT 3943/4885ESR1 4141/4885ESR2 2349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.