SCHEMBL23919938

SCHEMBL23919938

Cc1c(Cc2ccc(O)c(O)c2C)ccc(O)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.47
TYR P14679 1/20 0.42
HTR1D P28221 1/20 0.40
HTR1B P28222 1/20 0.40
HSPA5 P11021 2/20 0.39
HIF1A Q16665 2/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 2/20 0.38
BLM P54132 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
MEN1 O00255 1/20 0.38
SLC22A1 O15245 1/20 0.38
USP2 O75604 1/20 0.38
LMNA P02545 1/20 0.38
HSP90AA1 P07900 1/20 0.38
CYP3A4 P08684 1/20 0.38
HSPD1 P10809 1/20 0.38
IDO1 P14902 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278600 0.83 KEAP1 (0.50) MAPTESR1ESR2MEN1KMT2A
SCHEMBL5678308 0.83 GABRA1 (0.46) AMY1ATYRESR1ESR2HSP90AA1
SCHEMBL4063406 0.82 TYR (0.44) AMY1ATYRHTR1DHTR1BHSPA5
SCHEMBL31244461 0.80 TYR (0.57) AMY1ATYRHSPA5HIF1AMAPT
SCHEMBL8470006 0.80 TYR (0.57) AMY1ATYRHSPA5HIF1AMAPT
SCHEMBL924120 0.80 HTR1D (0.56) AMY1ATYRHTR1DHTR1BHSPA5
SCHEMBL29679737 0.80 HTR1D (0.56) AMY1ATYRHTR1DHTR1BHSPA5
SCHEMBL5195485 0.79 TYR (0.52) TYR
SCHEMBL29367192 0.78 SHBG (0.42) AMY1ATYRHTR1DHTR1BHSPA5
SCHEMBL265021 0.78 TAAR1 (0.47) TYRHIF1AMAPTBLMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572442-B2 Compound, polyimide resin and method of producing the same, photosensitive resin composition, patterning method and method of forming cured film, interlayer insulating film, surface protective film, and electronic component INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2023-02-07 US disclosed
US-20210317270-A1 NOVEL COMPOUND, POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572442-B2 Compound, polyimide resin and method of producing the same, photosensitive resin composition, patterning method and method of forming cured film, interlayer insulating film, surface protective film, and electronic component BRIX1, RBX1, HAX1 AMY1A 3338/4885TYR 1809/4885HTR1D 641/4885
US-20210317270-A1 NOVEL COMPOUND, POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT BRIX1, HAX1, RBX1 AMY1A 3073/4885TYR 1727/4885HTR1D 562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.