Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2094079 | 0.87 | ALDH1A1 (0.48) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL16119586 | 0.82 | ALDH1A1 (0.45) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL16240433 | 0.78 | TDP1 (0.40) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL27851425 | 0.78 | ALDH1A1 (0.40) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL7528740 | 0.78 | GAA (0.46) | ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL21461560 | 0.78 | GAA (0.45) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL13458993 | 0.75 | LMNA (0.38) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL2553022 | 0.75 | CXCL8 (0.49) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL31333015 | 0.75 | CXCL8 (0.49) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL15427843 | 0.73 | ALOX12 (0.38) | ALDH1A1TDP1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132921-A1 | SPIRO-INDOLE DERIVATIVES FOR THE TREATMENT OF PARASITIC DISEASES | NOVARTIS AG (CH) | 2009-11-05 | — | — | WO | disclosed |