SCHEMBL2095347

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2095343	0.89	ABCB1 (0.41)	ABCB1PRKDCPI4KBRAB9AALDH1A1
	SCHEMBL2098329	0.85	TP53 (0.38)	ALDH1A1LMNAMAPTHTTSMN1; SMN2
	SCHEMBL5016084	0.84	ALDH1A1 (0.50)	PI4KBALDH1A1LMNAMAPTHTT
	SCHEMBL27645051	0.83	PRKDC (0.48)	ABCB1PRKDCRAB9AALDH1A1LMNA
	SCHEMBL2090873	0.81	PDE3B (0.46)	MALT1
	SCHEMBL2098328	0.73	TP53 (0.38)	ALDH1A1LMNAMAPTHTTSMN1; SMN2
	SCHEMBL2093006	0.73	PRKDC (0.51)	ABCB1PRKDCRAB9AALDH1A1LMNA
	SCHEMBL5016083	0.73	ALDH1A1 (0.51)	PI4KBRAB9AALDH1A1LMNAMAPT
	SCHEMBL25758964	0.69	ABCB1 (0.61)	ABCB1RAB9AALDH1A1LMNAMAPT
	SCHEMBL3367454	0.69	CA2 (0.59)	ABCB1ALDH1A1LMNAMAPK1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.