Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016083 | 0.89 | ALDH1A1 (0.51) | ALDH1A1KDM4EKMT2ANPSR1MAPT | |
| SCHEMBL5011868 | 0.84 | DRD4 (0.41) | ALDH1A1KDM4ENPSR1MAPTSMN1; SMN2 | |
| SCHEMBL27644661 | 0.82 | DRD2 (0.52) | ALDH1A1KDM4EKMT2ANPSR1MAPT | |
| SCHEMBL2090873 | 0.77 | PDE3B (0.46) | — | |
| SCHEMBL5544199 | 0.75 | ALDH1A1 (0.63) | ALDH1A1KDM4EKMT2ANPSR1MAPT | |
| SCHEMBL1600111 | 0.73 | KMT2A (0.65) | ALDH1A1KDM4EKMT2ATSHRALOX15 | |
| SCHEMBL2095343 | 0.73 | ABCB1 (0.41) | ALDH1A1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL5011858 | 0.72 | DRD4 (0.44) | ALDH1A1KDM4EMAPTSMN1; SMN2DRD2 | |
| SCHEMBL5016098 | 0.72 | PIK3C2B (0.46) | ALDH1A1KDM4EKMT2ANPSR1MAPT | |
| SCHEMBL5544192 | 0.70 | ALDH1A1 (0.63) | ALDH1A1KDM4EKMT2ANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |