Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12809682 | 0.78 | GABRP (0.37) | — | |
| SCHEMBL23641806 | 0.77 | — | — | |
| SCHEMBL20628581 | 0.77 | MMP1 (0.31) | — | |
| SCHEMBL24568579 | 0.77 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL24568580 | 0.77 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL20803525 | 0.75 | — | — | |
| SCHEMBL24974729 | 0.73 | CHRNB2 (0.33) | CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL19221397 | 0.70 | ALDH1A1 (0.36) | CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL17171319 | 0.70 | FAAH (0.34) | CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL18950192 | 0.70 | CHRNB2 (0.31) | CHRNB2CHRNB4CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262789-A1 | ANTITUMOR COMPOUND AND USE THEREOF | 明慧医药（杭州）有限公司 | 2022-12-22 | — | — | WO | disclosed |
| EP-3769787-A1 | CONJUGATES OF CYSTEINE ENGINEERED ANTIBODIES | ImmunoGen, Inc. (US) | 2021-01-27 | — | — | EP | disclosed |
| EP-3313845-B1 | CONJUGATES OF CYSTEINE ENGINEERED ANTIBODIES | IMMUNOGEN INC (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-2961435-B1 | CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS | IMMUNOGEN INC (US) | 2019-05-01 | — | — | EP | disclosed |