Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125543 | 0.86 | ALDH1A3 (0.64) | ALDH1A3KMT2APARP10ALDH1A1POLB | |
| Hydrogen Peroxide SCHEMBL28902806 | 0.80 | KMT2A (0.70) | ALDH1A3KMT2APARP10ALDH1A1POLB | |
| SCHEMBL2643806 | 0.80 | PARP10 (0.41) | ALDH1A3KMT2APARP10ALDH1A1POLB | |
| SCHEMBL6282894 | 0.78 | ALDH1A3 (0.56) | ALDH1A3KMT2APARP10ALDH1A1POLB | |
| SCHEMBL197284 | 0.78 | ALDH1A3 (0.56) | ALDH1A3KMT2APARP10ALDH1A1POLB | |
| SCHEMBL2091722 | 0.77 | ACACB (0.40) | ALDH1A3POLBGAASMN1; SMN2FFAR4 | |
| SCHEMBL2215535 | 0.77 | CYP1A2 (0.33) | ALDH1A3KMT2APARP10MAPK1CYP1A2 | |
| SCHEMBL104201 | 0.76 | ALDH1A3 (0.54) | ALDH1A3KMT2APARP10ALDH1A1POLB | |
| SCHEMBL22325682 | 0.76 | ALDH1A1 (0.54) | ALDH1A3KMT2APARP10ALDH1A1POLB | |
| SCHEMBL29171514 | 0.76 | ALDH1A3 (0.54) | ALDH1A3KMT2APARP10ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487553-B2 | Boranophosphate analogues of cyclic nucleotides | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2016-11-08 | — | — | US | claimed |
| EP-2691403-B1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG LIFE SCIENCE INST FORSCHUNGSLABOR UND BIOCHEMICA VERTRIEB GMBH (DE) | 2016-05-18 | — | — | EP | claimed |
| EP-1511757-B1 | NEW COMPOUNDS FOR MODULATING THE ACTIVITY OF EXCHANGE PROTEINS DIRECTLY ACTIVATED BY CAMP (EPACS) | UNIV MEDISCH CENTRUM UTRECHT (NL) | 2015-11-04 | — | — | EP | claimed |
| US-20140088033-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2014-03-27 | — | — | US | claimed |
| EP-2691403-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG Life Science Institute Forschungslabor Und Biochemica-Vertrieb GmbH (DE) | 2014-02-05 | — | — | EP | claimed |
| WO-2012130829-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2012-10-04 | — | — | WO | claimed |
| US-7906491-B2 | Compounds for modulating the activity of exchange proteins directly activated by cAMP (Epacs) | UNIVISITAIR MEDISCH CENTRUM UTRECHT (NL) | 2011-03-15 | — | — | US | claimed |
| WO-2007006544-A2 | CYCLIC ADENOSINE MONOPHOSPHATE COMPOUNDS FOR THE TREATMENT OF IMMUNE-RELATED DISORDERS | VRIJE UNIVERSITEIT BRUSSEL (BE) | 2007-01-18 | — | — | WO | claimed |
| US-20060100166-A1 | Compounds for modulating the activity of exchange proteins directly activated by camp (epacs) | KYLIX B.V. (NL) | 2006-05-11 | — | — | US | claimed |
| EP-1511757-A1 | NEW COMPOUNDS FOR MODULATING THE ACTIVITY OF EXCHANGE PROTEINS DIRECTLY ACTIVATED BY CAMP (EPACS) | Kylix B.V. (NL) | 2005-03-09 | — | — | EP | claimed |
| WO-2003104250-A1 | NEW COMPOUNDS FOR MODULATING THE ACTIVITY OF EXCHANGE PROTEINS DIRECTLY ACTIVATED BY CAMP (EPACS) | KYLIX, B. V. (NL) | 2003-12-18 | — | — | WO | claimed |
| CN-113711113-B | Optical material, polymerizable composition for optical material, plastic lens, goggles, infrared sensor, and infrared camera | 三井化学株式会社 | 2023-07-28 | — | — | CN | disclosed |
| CN-113711113-A | Optical material, polymerizable composition for optical material, plastic lens, eyewear, infrared sensor, and infrared camera | 三井化学株式会社 | 2021-11-26 | — | — | CN | disclosed |
| US-9487553-B2 | Boranophosphate analogues of cyclic nucleotides | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2016-11-08 | — | — | US | disclosed |
| EP-2691403-B1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG LIFE SCIENCE INST FORSCHUNGSLABOR UND BIOCHEMICA VERTRIEB GMBH (DE) | 2016-05-18 | — | — | EP | disclosed |
| US-4716232-A | 1-(vinyl phosphonate adduct) pyrazolidinones | ELI LILLY AND COMPANY (US) | 1987-12-29 | — | — | US | disclosed |
| EP-0203722-A1 | Bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-12-03 | — | — | EP | disclosed |
| EP-0203723-A1 | 2,3-(dihydro)bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-12-03 | — | — | EP | disclosed |
| EP-0202794-A1 | 7-Substituted-2,3-(Dihydro) bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-26 | — | — | EP | disclosed |
| EP-0202046-A1 | 7-Substituted bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100166-A1 | Compounds for modulating the activity of exchange proteins directly activated by camp (epacs) | RAPGEF3, CREB1, PDE4C | ALDH1A3 3542/4885KMT2A 4454/4885PARP10 1387/4885 |
| US-20140088033-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | NT5C2, NT5E, ENPP3 | ALDH1A3 1046/4885KMT2A 4464/4885PARP10 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.