SCHEMBL20964323

SCHEMBL20964323

CN1C(=O)c2ccc3c4ncc5c6c(ccc(c7ncc(c2c37)C1=O)c64)C(=O)N(C)C5=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.44
▸ KMT2A Q03164 5/20 0.44
▸ ALDH1A1 P00352 4/20 0.44
▸ USP2 O75604 2/20 0.44
▸ KEAP1 Q14145 2/20 0.44
▸ NFE2L2 Q16236 2/20 0.44
▸ HPGD P15428 2/20 0.44
▸ ATM Q13315 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ POLB P06746 1/20 0.41
▸ PRMT1 Q99873 1/20 0.41
▸ TERT O14746 7/20 0.39
▸ STAT3 P40763 1/20 0.37
▸ HIF1A Q16665 1/20 0.37
▸ CASP3 P42574 1/20 0.36
▸ L3MBTL1 Q9Y468 3/20 0.34
▸ MAPT P10636 2/20 0.34
▸ HSD17B10 Q99714 2/20 0.34
▸ ALOX15 P16050 1/20 0.34
▸ APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22746164 0.87 KDM4E (0.48) MEN1KMT2AALDH1A1USP2KEAP1
SCHEMBL24603666 0.83 ALDH1A1 (0.51) MEN1KMT2AALDH1A1KDM4EPOLB
SCHEMBL22606004 0.81 TERT (0.40) MEN1KMT2AALDH1A1KEAP1NFE2L2
SCHEMBL20964322 0.80 STAT3 (0.47) MEN1KMT2AALDH1A1USP2ATM
SCHEMBL710594 0.78 TERT (0.56) MEN1KMT2AALDH1A1USP2KEAP1
SCHEMBL9968958 0.78 TERT (0.56) MEN1KMT2AALDH1A1USP2KEAP1
SCHEMBL12170761 0.78 TERT (0.56) MEN1KMT2AALDH1A1USP2KEAP1
SCHEMBL9968962 0.78 TERT (0.56) MEN1KMT2AALDH1A1USP2KEAP1
SCHEMBL29355182 0.78 TERT (0.56) MEN1KMT2AALDH1A1USP2KEAP1
SCHEMBL127059 0.78 MEN1 (0.55) MEN1KMT2AALDH1A1USP2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025901-A1 METHOD FOR PRODUCING CYCLIC IMIDE COMPOUND, COMPOSITION, AND COMPOUND FUJIFILM CORPORATION (JP) 2024-01-25 — — US disclosed
US-20230157038-A1 ANALOG AMPLIFIER CHIRACOL CO., LTD. (JP) 2023-05-18 — — US disclosed
US-20210351363-A1 ORGANIC THIN FILM TRANSISTOR, ORGANIC SEMICONDUCTOR FILM, COMPOUND, ORGANIC THIN FILM TRANSISTOR-FORMING COMPOSITION, AND METHOD OF MANUFACTURING ORGANIC THIN FILM TRANSISTOR FUJIFILM CORPORATION (JP) 2021-11-11 — — US disclosed
US-20190131546-A1 ORGANIC THIN FILM TRANSISTOR, ORGANIC SEMICONDUCTOR FILM, COMPOUND, ORGANIC THIN FILM TRANSISTOR-FORMING COMPOSITION, AND METHOD OF MANUFACTURING ORGANIC THIN FILM TRANSISTOR FUJIFILM CORPORATION (JP) 2019-05-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190131546-A1 ORGANIC THIN FILM TRANSISTOR, ORGANIC SEMICONDUCTOR FILM, COMPOUND, ORGANIC THIN FILM TRANSISTOR-FORMING COMPOSITION, AND METHOD OF MANUFACTURING ORGANIC THIN FILM TRANSISTOR OSTC, FTO, PORCN MEN1 919/4885KMT2A 815/4885ALDH1A1 3800/4885
US-20240025901-A1 METHOD FOR PRODUCING CYCLIC IMIDE COMPOUND, COMPOSITION, AND COMPOUND INF2, NISCH, ITPA MEN1 91/4885KMT2A 2582/4885ALDH1A1 2802/4885
US-20210351363-A1 ORGANIC THIN FILM TRANSISTOR, ORGANIC SEMICONDUCTOR FILM, COMPOUND, ORGANIC THIN FILM TRANSISTOR-FORMING COMPOSITION, AND METHOD OF MANUFACTURING ORGANIC THIN FILM TRANSISTOR OSTC, FTO, PORCN MEN1 919/4885KMT2A 815/4885ALDH1A1 3800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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