Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 6/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20964681 | 0.88 | LMNA (0.73) | SMN1; SMN2LMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL20964589 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL20964609 | 0.85 | ALDH1A1 (0.61) | SMN1; SMN2LMNAALDH1A1TSHRAR | |
| SCHEMBL19747102 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL20964660 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL20964706 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL19744985 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL20964627 | 0.82 | LMNA (0.62) | SMN1; SMN2LMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL20964600 | 0.82 | TSHR (0.56) | SMN1; SMN2LMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL20964554 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851096-B2 | Aryl and heteroaryl amides for use as anti-proliferative, anti-thrombotic, and anti-viral agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-12-01 | — | — | US | disclosed |
| US-20190127361-A1 | Therapeutic Compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127361-A1 | Therapeutic Compounds | SDHA, SLC10A1, SERPINC1 | SMN1; SMN2 263/4885LMNA 1413/4885ALDH1A1 141/4885 |
| US-10851096-B2 | Aryl and heteroaryl amides for use as anti-proliferative, anti-thrombotic, and anti-viral agents | SERPINC1, F12, RPL35 | SMN1; SMN2 2477/4885LMNA 897/4885ALDH1A1 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.