Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | AR | P10275 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20964616 | 0.88 | ALDH1A1 (0.73) | TSHRALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL20964609 | 0.85 | ALDH1A1 (0.61) | TSHRALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL20965422 | 0.84 | SMN1; SMN2 (0.60) | TSHRALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL20965335 | 0.83 | L3MBTL1 (0.66) | TSHRALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL20964673 | 0.82 | MAPT (0.58) | TSHRALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL20964632 | 0.82 | SMN1; SMN2 (0.57) | TSHRALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL20964644 | 0.81 | SMN1; SMN2 (0.71) | TSHRALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL20964660 | 0.81 | SMN1; SMN2 (0.63) | TSHRALDH1A1SMN1; SMN2LMNAAR | |
| SCHEMBL20964706 | 0.81 | SMN1; SMN2 (0.56) | TSHRALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL20964627 | 0.80 | LMNA (0.62) | TSHRALDH1A1SMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851096-B2 | Aryl and heteroaryl amides for use as anti-proliferative, anti-thrombotic, and anti-viral agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-12-01 | — | — | US | disclosed |
| US-20190127361-A1 | Therapeutic Compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127361-A1 | Therapeutic Compounds | SDHA, SLC10A1, SERPINC1 | TSHR 3423/4885ALDH1A1 141/4885SMN1; SMN2 263/4885 |
| US-10851096-B2 | Aryl and heteroaryl amides for use as anti-proliferative, anti-thrombotic, and anti-viral agents | SERPINC1, F12, RPL35 | TSHR 2794/4885ALDH1A1 870/4885SMN1; SMN2 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.