Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512325 | 0.84 | CTSK (0.46) | CTSKSMN1; SMN2USP2PREPCTSS | |
| SCHEMBL9512357 | 0.84 | CTSK (0.46) | CTSKSMN1; SMN2USP2PREPCTSS | |
| SCHEMBL9937144 | 0.81 | SMN1; SMN2 (0.45) | CTSKSMN1; SMN2USP2PREPCTSS | |
| SCHEMBL1503616 | 0.81 | CTSK (0.45) | CTSKSMN1; SMN2USP2PREPCTSS | |
| Tetrahydrofuran SCHEMBL28201359 | 0.78 | CTSK (0.50) | CTSKSMN1; SMN2PREPCTSSCTSL | |
| Tetrahydrofuran SCHEMBL28201360 | 0.78 | CTSK (0.50) | CTSKSMN1; SMN2PREPCTSSCTSL | |
| SCHEMBL9512342 | 0.78 | CTSL (0.38) | CTSKSMN1; SMN2USP2PREPCTSS | |
| SCHEMBL23050302 | 0.76 | CTSK (0.53) | CTSKSMN1; SMN2USP2PREPCTSS | |
| SCHEMBL3820779 | 0.75 | CTSK (0.47) | CTSKSMN1; SMN2USP2CTSSCTSL | |
| Fluoride SCHEMBL7360444 | 0.75 | CTSK (0.59) | CTSKPREPCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163956-B2 | Inhibitors of GLYT1 transporters | MERCK SHARP & DOHME CORP. (US) | 2012-04-24 | — | — | US | disclosed |