Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.37 |
| ▸ | CTSB | P07858 | 3/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27479107 | 0.81 | CTSL (0.37) | CTSLCTSKCTSBPREPELANE | |
| SCHEMBL2096750 | 0.78 | CTSK (0.45) | CTSLCTSKCTSBPREPUSP2 | |
| SCHEMBL9512325 | 0.76 | CTSK (0.46) | CTSLCTSKCTSBPREPUSP2 | |
| SCHEMBL9512357 | 0.76 | CTSK (0.46) | CTSLCTSKCTSBPREPUSP2 | |
| SCHEMBL28861849 | 0.69 | DPP7 (0.37) | SMN1; SMN2TSHRKDM4E | |
| SCHEMBL5011681 | 0.67 | CTSS (0.50) | CTSLCTSKKMT2AKDM4ECTSS | |
| SCHEMBL27485069 | 0.67 | CTSS (0.50) | CTSLCTSKKMT2AKDM4ECTSS | |
| Proline SCHEMBL8645011 | 0.67 | PSENEN (0.47) | CTSLCTSKKMT2ACTSDCTSS | |
| SCHEMBL8645014 | 0.67 | CTSS (0.46) | CTSLCTSKKMT2ACTSS | |
| SCHEMBL23050302 | 0.67 | CTSK (0.53) | CTSLCTSKCTSBPREPELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254545-B1 | DIAMINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-06 | — | — | EP | disclosed |
| EP-0254545-A2 | Diamine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-27 | — | — | EP | disclosed |