SCHEMBL20968147

SCHEMBL20968147

CS(C)(C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.46
HTR2A P28223 1/20 0.41
POLB P06746 2/20 0.39
ACHE P22303 3/20 0.38
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
CHRM1 P11229 1/20 0.38
DRD1 P21728 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38
OPRM1 P35372 1/20 0.38
DRD3 P35462 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
KMT2A Q03164 3/20 0.36
BCHE P06276 2/20 0.36
MEN1 O00255 2/20 0.36
SLC22A2 O15244 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19042320 0.84 GPR3 (0.46) GPR3HTR2APOLBACHECHRM2
SCHEMBL17308141 0.80 GPR3 (0.43) GPR3HTR2APOLBACHECHRM2
SCHEMBL18827258 0.77 GPR3 (0.40) GPR3HTR2APOLBACHECHRM2
SCHEMBL21065432 0.75 GPR3 (0.32) GPR3HTR2ASLC6A2SLC6A4SLC6A3
SCHEMBL22402767 0.74 GPR3 (0.46) GPR3HTR2APOLBACHECHRM2
SCHEMBL22148984 0.73 PTGS2 (0.31) PTGS2
SCHEMBL22078508 0.72 PARG (0.37) GPR3HTR2APOLBACHECHRM2
SCHEMBL4327573 0.70 CA1 (0.41) GPR3HTR2APOLBKMT2ABCHE
SCHEMBL5008319 0.70 CA1 (0.41) GPR3HTR2APOLBKMT2ABCHE
SCHEMBL2319486 0.70 NCOR2 (0.42) GPR3HTR2APOLBKMT2ABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10954321-B2 High-density ethylene-based polymer using supported hybrid metallocene catalyst, and manufacturing method therefor HANWHA CHEMICAL CORPORATION (KR) 2021-03-23 US disclosed
US-20190169325-A1 HIGH-DENSITY ETHYLENE-BASED POLYMER USING SUPPORTED HYBRID METALLOCENE CATALYST, AND MANUFACTURING METHOD THEREFOR HANWHA CHEMICAL CORPORATION (KR) 2019-06-06 US disclosed
US-20190127503-A1 HIGH-DENSITY ETHYLENE-BASED POLYMER USING HYBRID SUPPORTED METALLOCENE CATALYST, AND PREPARATION METHOD HANWHA CHEMICAL CORPORATION (KR) 2019-05-02 US disclosed