SCHEMBL21065432

SCHEMBL21065432

CS(C)(C1Cc2c(c3ccccc3c3ccccc23)C1)C1c2ccccc2-c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21065416 0.82
SCHEMBL20968147 0.75 GPR3 (0.46) GPR3SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL20968137 0.68 POLB (0.36) SLC6A2SLC6A4SLC6A3
SCHEMBL19042320 0.67 GPR3 (0.46) GPR3SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL21065559 0.66 KDM4E (0.41) SLC6A4
SCHEMBL17308141 0.64 GPR3 (0.43) GPR3SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL18827258 0.61 GPR3 (0.40) GPR3SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL7634193 0.61 EP300 (0.36) SLC6A2
SCHEMBL22402767 0.59 GPR3 (0.46) GPR3SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL7633875 0.59 ACHE (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10975184-B2 High-density ethylene-based polymer using hybrid supported metallocene catalyst and pipe using same HANWHA CHEMICAL CORPORATION (KR) 2021-04-13 US disclosed
US-10954321-B2 High-density ethylene-based polymer using supported hybrid metallocene catalyst, and manufacturing method therefor HANWHA CHEMICAL CORPORATION (KR) 2021-03-23 US disclosed
US-20190169325-A1 HIGH-DENSITY ETHYLENE-BASED POLYMER USING SUPPORTED HYBRID METALLOCENE CATALYST, AND MANUFACTURING METHOD THEREFOR HANWHA CHEMICAL CORPORATION (KR) 2019-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10975184-B2 High-density ethylene-based polymer using hybrid supported metallocene catalyst and pipe using same EEF1E1, EPN1, EEF1A1 GPR3 4771/4885SLC6A2 4768/4885SLC6A4 4490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.