Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19658319 | 0.89 | SMN1; SMN2 (0.36) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL1241407 | 0.84 | CHRM5 (0.39) | MEN1KMT2ADDB1CRBN | |
| SCHEMBL26382118 | 0.83 | SMN1; SMN2 (0.33) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL29673006 | 0.83 | CHRM5 (0.38) | MEN1KMT2ADDB1CRBN | |
| SCHEMBL17756756 | 0.81 | ALOX15 (0.41) | KMT2AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL19643061 | 0.81 | GLA (0.49) | KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12038457 | 0.78 | CHRM5 (0.35) | HSD17B10 | |
| SCHEMBL14522328 | 0.78 | CHRM5 (0.35) | HSD17B10 | |
| SCHEMBL16250588 | 0.78 | MGLL (0.30) | SMN1; SMN2 | |
| SCHEMBL43576 | 0.77 | PSMB8 (0.35) | KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3196200-B1 | 2-AMINOTHIAZOLE DERIVATIVES OR SALT THEREOF AS MUSCARINIC M3 LIGANDS FOR THE TREATMENT OF BLADDER DISEASES | ASTELLAS PHARMA INC (JP) | 2019-05-08 | — | — | EP | disclosed |