SCHEMBL28610259

SCHEMBL28610259

N#Cc1ccc(Nc2ncncn2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.51
TDO2 P48775 1/20 0.49
ABCG2 Q9UNQ0 3/20 0.47
CDC7 O00311 1/20 0.47
KCNH2 Q12809 1/20 0.47
SCN5A Q14524 1/20 0.47
SCN9A Q15858 1/20 0.47
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CTSK P43235 2/20 0.42
CTSS P25774 1/20 0.42
CYP2C19 P33261 3/20 0.42
CYP11B2 P19099 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP11B1 P15538 1/20 0.42
CYP3A4 P08684 1/20 0.42
IKBKB O14920 1/20 0.42
ABCB1 P08183 1/20 0.41
DHODH Q02127 1/20 0.41
CTSL P07711 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1881253 0.85 CDC7 (0.61) SYKABCG2CDC7KCNH2SCN5A
SCHEMBL10382992 0.83 RAB9A (0.44) SYKKCNH2SCN5ASCN9AMEN1
SCHEMBL1741981 0.82 KCNH2 (0.55) SYKTDO2ABCG2CDC7KCNH2
SCHEMBL21914834 0.79 CTSK (0.58) SYKABCG2CDC7KCNH2SCN5A
SCHEMBL31235584 0.79 CDC7 (0.63) SYKABCG2CDC7MAOBGRM5
SCHEMBL28619400 0.79 CDC7 (0.63) SYKABCG2CDC7MAOBGRM5
SCHEMBL27637976 0.78 SYK (0.56) SYKTDO2KCNH2SCN5ASCN9A
SCHEMBL1182248 0.78 SYK (0.52) SYKABCG2CDC7KCNH2SCN5A
SCHEMBL395539 0.76 CA2 (0.52) SYKABCG2MEN1KMT2AABCB1
SCHEMBL8329412 0.74 CYP19A1 (0.52) SYKTDO2ABCG2SCN9ACYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113248426-B Heterocyclic triarylamine compound and organic photoelectric device containing same 浙江华显光电科技有限公司 2024-10-18 CN disclosed
CN-110054776-B Covalent organic microporous polymer containing triazine ring and preparation method and application thereof 湘潭大学 2021-08-31 CN disclosed
CN-113248426-A Heterocyclic triarylamine compound and organic photoelectric device containing same 浙江华显光电科技有限公司 2021-08-13 CN disclosed