⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20980415 | 0.88 | — | — | |
| SCHEMBL24012402 | 0.78 | CNR2 (0.32) | — | |
| SCHEMBL22375504 | 0.78 | ALB (0.32) | — | |
| SCHEMBL22375760 | 0.72 | ADRB2 (0.31) | — | |
| SCHEMBL13539965 | 0.71 | NOS1 (0.40) | — | |
| SCHEMBL22375469 | 0.71 | FOLH1 (0.33) | — | |
| SCHEMBL13539964 | 0.70 | CHRM2 (0.47) | — | |
| SCHEMBL24012407 | 0.69 | CNR2 (0.32) | — | |
| SCHEMBL16920503 | 0.69 | LTA4H (0.46) | — | |
| SCHEMBL16574757 | 0.69 | LTA4H (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190134214-A1 | GLP-1 Receptor Ligand Moiety Conjugated Oligonucleotides and Uses Thereof | ASTRAZENECA AB (SE) | 2019-05-09 | — | — | US | disclosed |