Glymidine

Glymidine

SCHEMBL209818

COCCOc1cnc(NS(=O)(=O)c2ccccc2)nc1.[NaH]

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.55
▸ LMNA P02545 1/20 0.53
▸ MAPK1 P28482 1/20 0.48
▸ ALDH1A1 P00352 5/20 0.47
▸ KMT2A Q03164 3/20 0.46
▸ KDM4E B2RXH2 2/20 0.46
▸ HTT P42858 1/20 0.46
▸ LIMK2 P53671 1/20 0.46
▸ NPSR1 Q6W5P4 1/20 0.46
▸ TSHR P16473 2/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ MAPT P10636 1/20 0.45
▸ PKM P14618 2/20 0.44
▸ CCR4 P51679 1/20 0.43
▸ F2 P00734 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glymidine SCHEMBL34389 0.99 TDP1 (0.56) TDP1LMNAMAPK1ALDH1A1KMT2A
Glymidine SCHEMBL27852481 0.97 TDP1 (0.55) TDP1LMNAMAPK1ALDH1A1KMT2A
SCHEMBL23567060 0.84 LMNA (0.73) TDP1LMNAALDH1A1KMT2ANPSR1
SCHEMBL11130757 0.80 LMNA (0.52) TDP1LMNAALDH1A1KMT2AKDM4E
SCHEMBL21753108 0.76 TSHR (0.60) TDP1LMNAALDH1A1KDM4ENPSR1
Acetohexamide SCHEMBL13723464 0.75 LMNA (0.60) TDP1LMNAALDH1A1KMT2ALIMK2
SCHEMBL18434115 0.75 KCNH3 (0.53) LMNAMAPK1KMT2ATSHRMEN1
Glymidine Sodium SCHEMBL29371260 0.74 L3MBTL1 (0.39) TDP1MAPK1ALDH1A1KMT2AHTT
SCHEMBL23555262 0.74 LIMK2 (0.64) LMNAALDH1A1KMT2AHTTLIMK2
SCHEMBL26806983 0.73 MAPT (0.50) TDP1LMNAMAPK1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 904 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2001450-B1 DIRECTLY COMPRESSIBLE COMPOSITE FOR ORALLY DISINTEGRATING TABLETS RUBICON RES PRIVATE LIMITED (IN) 2019-01-30 — — EP claimed
US-20150051289-A1 LIQUID FORMULATIONS OF HYPOGLYCAEMIC SULFONAMIDES AMMTEK (FR) 2015-02-19 — — US claimed
US-20150050371-A1 Extract Formulations of Rhodamnia Cinerea And Uses Thereof BIOTROPICS MALAYSIA BERHAD (MY) 2015-02-19 — — US claimed
CN-101460150-B Directly compressible compound for orally disintegrating tablets RUBICON RES PRIVATE LTD 2014-02-12 — — CN claimed
WO-2013133685-A1 EXTRACT FORMULATIONS OF RHODAMNIA CINEREA AND USES THEREOF BIOTROPICS MALAYSIA BERHAD (MY) 2013-09-12 — — WO claimed
CN-102885798-A Orally disintegrating tablet CHENGDU KANGHONG PHARMACEUTICAL GROUP CO LTD 2013-01-23 — — CN claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 — — US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 — — US claimed
US-20090208576-A1 Orally Disintegrating Tablets RUBICON RESEARCH PRIVATE LIMITED (IN) 2009-08-20 — — US claimed
CN-101460150-A Directly compressible compound for orally disintegrating tablets RUBICON RES PRIVATE LTD (IN) 2009-06-17 — — CN claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 — — US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 — — US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 — — US claimed
EP-0580860-B2 METHOD OF MANUFACTURING SOLID DISPERSION NIPPON SHINYAKU CO LTD (JP) 2004-12-15 — — EP claimed
EP-1334114-A2 TRANSCOBALAMIN BINDING CONJUGATES USEFUL FOR TREATING ABNORMAL CELLULAR PROLIFERATION MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2003-08-13 — — EP claimed
US-20020151525-A1 Transcobalamin receptor binding conjugates useful for treating abnormal cellular proliferation COLLINS DOUGLAS A (US) 2002-10-17 — — US claimed
WO-2002055530-A2 TRANSCOBALAMIN BINDING CONJUGATES USEFUL FOR TREATING ABNORMAL CELLULAR PROLIFERATION MAYO FOUNDATION (US) 2002-07-18 — — WO claimed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 — — US claimed
US-5700410-A Method of manufacturing wax matrices NIPPON SHINYAKU CO., LTD. (JP) 1997-12-23 — — US claimed
EP-0580860-B1 METHOD OF MANUFACTURING SOLID DISPERSION NIPPON SHINYAKU CO LTD (JP) 1997-10-22 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151525-A1 Transcobalamin receptor binding conjugates useful for treating abnormal cellular proliferation PCNA, MKI67, SLC19A1 TDP1 1651/4885LMNA 262/4885MAPK1 3491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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