Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | CA2 | P00918 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | TYR | P14679 | 1/20 | 0.72 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HMGCR | P04035 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butylated Hydroxytoluene SCHEMBL11647738 | 1.00 | ALDH1A1 (0.72) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL994118 | 0.85 | ALDH1A1 (0.82) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL453824 | 0.85 | SMN1; SMN2 (1.00) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL3950 | 0.85 | SMN1; SMN2 (1.00) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL125095 | 0.83 | SMN1; SMN2 (0.78) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL4170581 | 0.83 | SMN1; SMN2 (0.95) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL9343307 | 0.83 | SMN1; SMN2 (0.95) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL20660368 | 0.83 | SMN1; SMN2 (0.95) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL9343306 | 0.83 | SMN1; SMN2 (0.95) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL11859223 | 0.83 | SMN1; SMN2 (0.95) | ALDH1A1CA2SMN1; SMN2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084790-B2 | Insoluble complex or solvate thereof, pharmaceutical composition and use thereof | Fruithy Holdings Limited (CN) | 2021-08-10 | — | — | US | claimed |
| CN-109996787-A | Slightly solubility compound or its solvate, pharmaceutical composition and its application | 合肥合源药业有限公司 | 2019-07-09 | — | — | CN | claimed |
| EP-3486233-A1 | POORLY SOLUBLE COMPLEX OR SOLVATE THEREOF, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | FRUITHY HOLDINGS LIMITED (CN) | 2019-05-22 | — | — | EP | claimed |
| CN-107848973-A | The dimethylaniline formyl piperidine crystal of 1 propyl group of S () 2 ', 6 ' and its sustained release preparation | 四川海思科制药有限公司 | 2018-03-27 | — | — | CN | claimed |
| US-11084790-B2 | Insoluble complex or solvate thereof, pharmaceutical composition and use thereof | Fruithy Holdings Limited (CN) | 2021-08-10 | — | — | US | disclosed |
| US-20210087144-A1 | INSOLUBLE COMPLEX OR SOLVATE THEREOF, PHARMACEUTICAL COMPOSTION AND USE THEREOF | Fruithy Holdings Limited (CN) | 2021-03-25 | — | — | US | disclosed |
| EP-3486233-B1 | POORLY SOLUBLE COMPLEX OR SOLVATE THEREOF, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | FRUITHY HOLDINGS LTD (CN) | 2021-01-27 | — | — | EP | disclosed |
| CN-110812365-A | Composition, preparation method and preparation thereof | 明特奇点医疗科技（北京）有限公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-110139862-A | It can be used as the bicyclic heterocycles derivative of ROMK channel inhibitor being substituted | 百时美施贵宝公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-109996787-A | Slightly solubility compound or its solvate, pharmaceutical composition and its application | 合肥合源药业有限公司 | 2019-07-09 | — | — | CN | disclosed |
| EP-3486233-A1 | POORLY SOLUBLE COMPLEX OR SOLVATE THEREOF, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | FRUITHY HOLDINGS LIMITED (CN) | 2019-05-22 | — | — | EP | disclosed |
| CN-106061967-B | The nicotinamide compounds replaced through heteroaryl | 百时美施贵宝公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-103860476-B | lutein water-soluble powder and preparation method thereof | 广州新济药业科技有限公司 | 2017-06-23 | — | — | CN | disclosed |
| CN-101772302-B | Boron-containing small molecules | ANACOR PHARMACEUTICALS INC | 2014-05-07 | — | — | CN | disclosed |
| CN-1809340-B | Pharmaceutical products | EURO CELTIQUE SA | 2013-07-10 | — | — | CN | disclosed |
| CN-101835377-A | Pyrazole compounds for controlling invertebrate pests | BASF SE | 2010-09-15 | — | — | CN | disclosed |
| CN-101772302-A | Boron-containing small molecules | ANACOR PHARMACEUTICALS INC | 2010-07-07 | — | — | CN | disclosed |
| CN-1809340-A | Pharmaceutical products | EURO CELTIQUE SA (LU) | 2006-07-26 | — | — | CN | disclosed |
| CN-1232593-C | Coating composition for modifying hard surfaces | PROCTER & GAMBLE (US) | 2005-12-21 | — | — | CN | disclosed |
| CN-1439041-A | Coating composition for modifying hard surfaces | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084790-B2 | Insoluble complex or solvate thereof, pharmaceutical composition and use thereof | SYMPK, GUCY1A1, CYP3A5 | ALDH1A1 1077/4885CA2 971/4885SMN1; SMN2 435/4885 |
| US-20210087144-A1 | INSOLUBLE COMPLEX OR SOLVATE THEREOF, PHARMACEUTICAL COMPOSTION AND USE THEREOF | TTR, CUL5, CUL3 | ALDH1A1 1869/4885CA2 949/4885SMN1; SMN2 838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.