Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7158984 | 0.83 | LMNA (0.50) | CA9CA12CA1CA2MAPT | |
| SCHEMBL1122453 | 0.79 | MAPT (0.40) | CA9CA12CA1CA2MAPT | |
| SCHEMBL3838626 | 0.76 | MAPT (0.38) | CA9CA12CA1CA2MAPT | |
| SCHEMBL8614472 | 0.75 | ACHE (0.38) | CA9CA12CA1CA2MAPT | |
| SCHEMBL994489 | 0.75 | MAPT (0.44) | CA9CA12CA1CA2MAPT | |
| SCHEMBL6737529 | 0.74 | — | — | |
| SCHEMBL11816254 | 0.74 | AHR (0.43) | MAPTLMNATDP1CYP3A4TSHR | |
| SCHEMBL1486292 | 0.74 | — | — | |
| SCHEMBL90928 | 0.74 | MMP12 (0.34) | MAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL13652506 | 0.74 | AHR (0.43) | MAPTKDM4ESMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070169287-A1 | P-diaminobenzene derivatives and dyes containing these compounds | THE PROCTER & GAMBLE COMPANY (US) | 2007-07-26 | — | — | US | claimed |
| EP-1311231-B1 | AGENT FOR COLOURING KERATIN-CONTAINING FIBRES COMPRISING AT LEAST ONE OXOCYCLOPENTENE DERIVATIVE | HENKEL KGAA (DE) | 2006-11-22 | — | — | EP | claimed |
| EP-1292271-B1 | AGENT FOR DYEING FIBRES CONTAINING KERATIN | HENKEL KGAA (DE) | 2006-11-08 | — | — | EP | claimed |
| EP-1432428-B1 | Agent for colouring fibres containing keratin | HENKEL KGAA (DE) | 2006-11-02 | — | — | EP | claimed |
| US-7125428-B2 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | WELLA AG (DE) | 2006-10-24 | — | — | US | claimed |
| EP-1139989-B1 | AGENT FOR COLORING KERATINACEOUS FIBERS | HENKEL KGAA (DE) | 2006-10-18 | — | — | EP | claimed |
| US-7056349-B2 | Agent containing quinonimine derivatives and used to color keratin fibres, and associated method | WELLA AG (DE) | 2006-06-06 | — | — | US | claimed |
| EP-1198457-B1 | QUATERNIZED AZAFLUORENONES AND THEIR USE IN AGENTS FOR DYING FIBERS CONTAINING KERATIN | HENKEL KGAA (DE) | 2005-12-14 | — | — | EP | claimed |
| US-6936077-B2 | 1,3-diamino-4-(aminomethyl)—benzene derivatives and colorants containing the said compounds | WELLA AG (DE) | 2005-08-30 | — | — | US | claimed |
| US-5683474-A | HAIR DYES AND OXIDATION DYE PRECURSOR WITH OXIDIZERS | L'OREAL (FR) | 1997-11-04 | — | — | US | claimed |
| US-5053052-A | Washfast, lightfast oxidation color dyes | L'OREAL (FR) | 1991-10-01 | — | — | US | claimed |
| EP-0241716-B1 | PROCESS AND COMPOSITION FOR OXIDATIVE HAIR DYEING | Wella Aktiengesellschaft (DE) | 1990-08-29 | — | — | EP | claimed |
| US-9102617-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-08-11 | — | — | US | disclosed |
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2013-05-02 | — | — | US | disclosed |
| US-20120197015-A1 | EPOXYCARBOXAMIDE COMPOUND, AZIDE COMPOUND, AND AMINO ALCOHOL COMPOUND, AND PROCESS FOR PREPARING a-KETO AMIDE COMPOUND USING THEM | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2012-08-02 | — | — | US | disclosed |
| US-8163943-B2 | Epoxycarboxamide compound, azide compound, and amino alcohol compound, and process for preparing α-keto amide compound using them | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2012-04-24 | — | — | US | disclosed |
| WO-1998005639-A1 | 1,2-DIARYLINDOLE AS COX-2 INHIBITORS | LABORATOIRES UPSA (FR) | 1998-02-12 | — | — | WO | disclosed |
| US-5494911-A | TREATING LEUKEMIA, SARCOMA, CARCINOMA, LYMPHOMA, SKIN CANCER | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-27 | — | — | US | disclosed |
| US-5384423-A | Intermediates for antiinflammatory agents | ROUSSEL-UCLAF (FR) | 1995-01-24 | — | — | US | disclosed |
| EP-0387360-A1 | CYANINE COMPOUNDS | ASAHI CHEMICAL CO., LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | RPS4X, RPS4Y1, MRPL21 | CA9 2779/4885CA12 4481/4885CA1 4586/4885 |
| US-20120197015-A1 | EPOXYCARBOXAMIDE COMPOUND, AZIDE COMPOUND, AND AMINO ALCOHOL COMPOUND, AND PROCESS FOR PREPARING a-KETO AMIDE COMPOUND USING THEM | AKR1C1, AKR1C4, AADAC | CA9 1323/4885CA12 1952/4885CA1 1795/4885 |
| US-20070169287-A1 | P-diaminobenzene derivatives and dyes containing these compounds | KRT18, DSP, DSG1 | CA9 1848/4885CA12 1005/4885CA1 1885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.