Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 13/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20983852 | 1.00 | ABHD6 (0.66) | ABHD6ALDH1A1ACACBTAAR1HPGD | |
| SCHEMBL20983766 | 0.80 | ABHD6 (1.00) | ABHD6ACACB | |
| SCHEMBL20983768 | 0.80 | ABHD6 (1.00) | ABHD6ACACB | |
| SCHEMBL20983813 | 0.76 | ABHD6 (1.00) | ABHD6 | |
| SCHEMBL20396184 | 0.73 | MGLL (0.40) | ABHD6ALDH1A1 | |
| SCHEMBL20396182 | 0.73 | MGLL (0.40) | ABHD6ALDH1A1 | |
| SCHEMBL18418209 | 0.73 | MGLL (0.50) | ABHD6ALDH1A1 | |
| SCHEMBL18423343 | 0.73 | MGLL (0.50) | ABHD6ALDH1A1 | |
| SCHEMBL19923359 | 0.72 | CA1 (0.50) | — | |
| SCHEMBL18422360 | 0.72 | CA1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662159-B2 | ABHD6 and dual ABHD6/MGL inhibitors and their uses | MAKSCIENTIFIC, LLC (US) | 2020-05-26 | — | — | US | disclosed |
| US-20190152917-A1 | ABHD6 AND DUAL ABHD6/MGL INHIBITORS AND THEIR USES | MAKSCIENTIFIC, LLC | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662159-B2 | ABHD6 and dual ABHD6/MGL inhibitors and their uses | ABHD6, FAAH, FAAH2 | ABHD6 1/4885ALDH1A1 630/4885ACACB 307/4885 |
| US-20190152917-A1 | ABHD6 AND DUAL ABHD6/MGL INHIBITORS AND THEIR USES | ABHD6, FAAH, FAAH2 | ABHD6 1/4885ALDH1A1 630/4885ACACB 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.