Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 5/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.36 |
| ▸ | PIK3R5 | Q8WYR1 | 3/20 | 0.36 |
| ▸ | PIK3R3 | Q92569 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20986933 | 1.00 | PARP1 (0.41) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL3554115 | 0.74 | HTR2C (0.49) | HTR2BHTR2CHTR2A | |
| SCHEMBL31246891 | 0.72 | PARP1 (0.45) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL31227444 | 0.72 | PARP1 (0.45) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL21614132 | 0.68 | PARP1 (0.59) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30366187 | 0.68 | PARP1 (0.59) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL24761857 | 0.67 | ADAM17 (0.39) | FFAR1FFAR4PER2CRY1CRY2 | |
| SCHEMBL6588816 | 0.67 | SLC18A3 (0.51) | PARP1HTR2BHTR6HTR2CHTR2A | |
| SCHEMBL23697537 | 0.66 | HTR2B (0.55) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL13595229 | 0.66 | KEAP1 (0.39) | HTR2BHTR2CPIK3CDPIK3R2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190152992-A1 | BENZODIOXANE DERIVATIVES AND THEIR PHARMACEUTICAL USE | ORION CORPORATION (FI) | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152992-A1 | BENZODIOXANE DERIVATIVES AND THEIR PHARMACEUTICAL USE | TBXA2R, ADRA2C, ADRB2 | PARP1 1967/4885HTR2B 80/4885HTR3E 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.