Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 7/20 | 0.63 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | MGLL | Q99685 | 2/20 | 0.54 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | PMM2 | O15305 | 1/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.50 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004530 | 0.87 | CASP3 (0.67) | CASP3FAAHMGLLG6PDPMM2 | |
| SCHEMBL29678965 | 0.78 | CASP3 (1.00) | CASP3FAAHMGLLG6PD | |
| SCHEMBL3143600 | 0.78 | CASP3 (1.00) | CASP3FAAHMGLLG6PD | |
| SCHEMBL16071405 | 0.78 | CASP3 (0.68) | CASP3FAAHMGLL | |
| SCHEMBL11278746 | 0.77 | CASP3 (0.74) | CASP3FAAHMGLLG6PD | |
| SCHEMBL17948304 | 0.77 | CASP3 (0.72) | CASP3FAAHMGLL | |
| SCHEMBL20937506 | 0.75 | CASP3 (0.59) | CASP3G6PD | |
| SCHEMBL358740 | 0.75 | FAAH (0.77) | CASP3FAAHMGLLG6PD | |
| SCHEMBL24836231 | 0.74 | FAAH (0.81) | CASP3FAAHMGLLG6PD | |
| SCHEMBL2963555 | 0.74 | CASP3 (0.68) | CASP3FAAHMGLLG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190135835-A1 | MK2 INHIBITORS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190135835-A1 | MK2 INHIBITORS AND USES THEREOF | MKNK2, DUSP2, MKNK1 | CASP3 3813/4885FAAH 2247/4885MGLL 1358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.