SCHEMBL3143600

SCHEMBL3143600

CCn1sc2ccccc2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 7/20 1.00
FAAH O00519 2/20 0.66
MGLL Q99685 2/20 0.66
G6PD P11413 1/20 0.58
KAT2A Q92830 1/20 0.55
KAT2B Q92831 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29678965 1.00 CASP3 (1.00) CASP3FAAHMGLLG6PDKAT2A
SCHEMBL358740 0.85 FAAH (0.77) CASP3FAAHMGLLG6PDKAT2A
SCHEMBL11278746 0.84 CASP3 (0.74) CASP3FAAHMGLLG6PDKAT2A
SCHEMBL17948304 0.84 CASP3 (0.72) CASP3FAAHMGLLKAT2AKAT2B
Alcohol SCHEMBL28664257 0.84 CASP3 (0.72) CASP3FAAHMGLLG6PDKAT2A
SCHEMBL16601156 0.82 FAAH (0.88) CASP3FAAHMGLLG6PDKAT2A
SCHEMBL203818 0.82 FAAH (0.88) CASP3FAAHMGLLG6PDKAT2A
SCHEMBL29370720 0.82 FAAH (0.88) CASP3FAAHMGLLG6PDKAT2A
SCHEMBL7630656 0.81 CASP3 (0.68) CASP3FAAHMGLLG6PDKAT2A
SCHEMBL3147758 0.81 FAAH (0.97) CASP3FAAHMGLLG6PDKAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399355-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. 2023-12-14 US disclosed
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof Lakewood Amedex, Inc. (US) 2023-10-24 US disclosed
US-20230242548-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-08-03 US disclosed
US-20230242548-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-08-03 US disclosed
WO-2023009785-A1 TEAD INHIBITORS AND USES THEREOF CEDILLA THERAPEUTICS, INC. (US) 2023-02-02 WO disclosed
US-20230026056-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. 2023-01-26 US disclosed
WO-2022202958-A1 NON-AQUEOUS SECONDARY BATTERY POLYMER COMPOSITION AND NON-AQUEOUS SECONDARY BATTERY 旭化成株式会社 2022-09-29 WO disclosed
CN-111269195-B Synthesis method for preparing saccharin 上海交通大学 2022-02-25 CN disclosed
EP-3943087-A1 HETEROARYL COMPOUNDS AND USES THEREOF Celgene CAR LLC (BM) 2022-01-26 EP disclosed
EP-2968337-B1 HETEROARYL COMPOUNDS AND USES THEREOF CELGENE CAR LLC (BM) 2021-07-21 EP disclosed
US-5059516-A Spectrally sensitized to near infared region with cyanine dye, (benz)isothiazole and bromo-nitro substituted alkanol KONICA CORPORATION (JP) 1991-10-22 US disclosed
US-5008150-A Hydrophilic colloid, amine salt or quarternary ammonium, ester of p-hydroxybenzoic acid; improved adhesion MITSUBISHI PAPER MILLS LIMITED (JP) 1991-04-16 US disclosed
US-4999282-A Layer of Spectrally Sensitized Light-Sensitive Silver Halide Emulsion KONICA CORPORATION (JP) 1991-03-12 US disclosed
EP-0342987-A1 Silver halide photographic material KONICA CORPORATION (JP) 1989-11-23 EP disclosed
EP-0331319-A1 Method for the formation of images KONICA CORPORATION (JP) 1989-09-06 EP disclosed
EP-0018100-B1 SUBSTITUTED AROMATIC BIOLOGICALLY ACTIVE COMPOUND, A PROCESS FOR ITS PREPARATION AND ITS USE AS BIOCIDE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-18 EP disclosed
US-4396413-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1983-08-02 US disclosed
US-4241214-A BACTERICIDE, FUNGICIDE AND ALGAECIDE ROHM AND HAAS COMPANY (US) 1980-12-23 US disclosed
US-4150026-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1979-04-17 US disclosed
US-4062946-A 3-ISOTHIAZOLONES ROHM AND HAAS COMPANY (US) 1977-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230026056-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF CAT, MPO, NISCH CASP3 279/4885FAAH 3823/4885MGLL 509/4885
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof CAT, MPO, NISCH CASP3 279/4885FAAH 3823/4885MGLL 509/4885
US-20230242548-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER KRAS, HRAS, NRAS CASP3 919/4885FAAH 3508/4885MGLL 2601/4885
US-20230399355-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF CAT, MPO, NISCH CASP3 279/4885FAAH 3823/4885MGLL 509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.