Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 6/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.39 |
| ▸ | CDK9 | P50750 | 6/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 6/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 6/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.39 |
| ▸ | CDK2 | P24941 | 5/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19091295 | 0.87 | CD274 (0.39) | HCAR3HCAR2FYNALDH1A1ALOX12 | |
| SCHEMBL19080615 | 0.83 | HCAR3 (0.41) | HCAR3HCAR2FYNDYRK3CCNT1 | |
| Hydrochloric Acid SCHEMBL3673299 | 0.73 | ALDH1A1 (0.63) | ALDH1A1ALOX12ADRA1A | |
| SCHEMBL7663658 | 0.71 | CXCR4 (0.35) | ALDH1A1ALOX12CDK2 | |
| SCHEMBL13256436 | 0.70 | KMT2A (0.55) | ALDH1A1CDK2 | |
| SCHEMBL8060845 | 0.69 | ALDH1A1 (0.55) | ALDH1A1ALOX12ADRA1A | |
| SCHEMBL3941703 | 0.69 | FYN (0.44) | HCAR3HCAR2FYNDYRK3CCNT1 | |
| SCHEMBL7902111 | 0.69 | FDPS (0.56) | HCAR3HCAR2ALDH1A1 | |
| SCHEMBL11418172 | 0.68 | ALDH1A1 (0.54) | ALDH1A1ALOX12ADRA1A | |
| SCHEMBL10706332 | 0.68 | ALDH1A1 (0.54) | ALDH1A1ALOX12ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696707-B2 | Polyene macrolide derivative | SHIONOGI & CO., LTD. (JP) | 2020-06-30 | — | — | US | disclosed |
| US-20190135847-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190135847-A1 | POLYENE MACROLIDE DERIVATIVE | ERG28, RPL23, RPL10 | HCAR3 2669/4885HCAR2 3377/4885FYN 3929/4885 |
| US-10696707-B2 | Polyene macrolide derivative | ERG28, RPL23, RPL10 | HCAR3 2669/4885HCAR2 3377/4885FYN 3929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.