Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.50 |
| ▸ | CA1 | P00915 | 11/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5644652 | 0.79 | NPC1 (0.51) | PPARGNPC1GAA | |
| SCHEMBL5646821 | 0.78 | NPC1 (0.50) | PPARGNPC1GAA | |
| SCHEMBL2774122 | 0.76 | CA2 (0.56) | CA2CA1 | |
| SCHEMBL20647086 | 0.73 | KDM4E (0.50) | CA2CA1GAA | |
| SCHEMBL31187732 | 0.72 | L3MBTL1 (0.48) | PPARGGAA | |
| SCHEMBL31359082 | 0.72 | L3MBTL1 (0.48) | PPARGGAA | |
| SCHEMBL13687222 | 0.72 | CA2 (0.50) | CA2CA1 | |
| SCHEMBL26896061 | 0.71 | CES2 (0.45) | PPARG | |
| SCHEMBL5648866 | 0.71 | LMNA (0.60) | PPARGNPC1GAA | |
| SCHEMBL11533341 | 0.71 | CA2 (0.46) | CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190134056-A1 | K-RAS MUTATIONS AND ANTAGONISTS | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOG (US) | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190134056-A1 | K-RAS MUTATIONS AND ANTAGONISTS | KRAS, NRAS, HRAS | CA2 4121/4885CA1 4648/4885PPARG 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.