Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | SERPINE1 | P05121 | 12/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12341340 | 0.79 | MAPT (0.67) | MAPTLMNAHTTL3MBTL1SERPINE1 | |
| SCHEMBL7091041 | 0.76 | LMNA (0.70) | MAPTLMNAHTTL3MBTL1SERPINE1 | |
| SCHEMBL20989755 | 0.76 | MAPT (0.56) | MAPTLMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL7087663 | 0.75 | SERPINE1 (0.89) | MAPTLMNAHTTL3MBTL1SERPINE1 | |
| SCHEMBL12341425 | 0.73 | MAPT (0.57) | MAPTLMNAHTTL3MBTL1SERPINE1 | |
| SCHEMBL19546473 | 0.73 | MAPT (0.64) | MAPTLMNAHTTL3MBTL1SERPINE1 | |
| SCHEMBL5329963 | 0.72 | MAPT (0.64) | MAPTLMNAHTTL3MBTL1SERPINE1 | |
| SCHEMBL7085648 | 0.72 | LMNA (0.64) | MAPTLMNAHTTL3MBTL1SERPINE1 | |
| SCHEMBL7084136 | 0.72 | SERPINE1 (0.81) | MAPTLMNAHTTL3MBTL1SERPINE1 | |
| SCHEMBL7091396 | 0.72 | SERPINE1 (1.00) | MAPTLMNAHTTL3MBTL1SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190134024-A1 | ANTAGONISTS OF THE THYROID-STIMULATING HORMONE RECEPTOR (TSHR) | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190134024-A1 | ANTAGONISTS OF THE THYROID-STIMULATING HORMONE RECEPTOR (TSHR) | TSHR, TRHR, THRA | MAPT 4654/4885LMNA 4762/4885HTT 1125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.