Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.63 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.63 |
| ▸ | SERPINE1 | P05121 | 13/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087900 | 0.82 | SERPINE1 (0.67) | SLC6A9SLC6A5SERPINE1MEN1KMT2A | |
| SCHEMBL29378218 | 0.81 | GAA (0.61) | LMNAMAPTHTTSLC6A9MEN1 | |
| SCHEMBL22465912 | 0.81 | GAA (0.61) | LMNAMAPTHTTSLC6A9MEN1 | |
| SCHEMBL853678 | 0.80 | CCNA2 (0.58) | LMNAHTTSLC6A9MEN1KMT2A | |
| SCHEMBL7089010 | 0.79 | MAPT (0.57) | LMNAMAPTHTTL3MBTL1SERPINE1 | |
| SCHEMBL28901655 | 0.78 | SLC6A9 (0.48) | LMNAHTTSLC6A9SLC6A5KMT2A | |
| SCHEMBL3932988 | 0.78 | SLC6A9 (1.00) | SLC6A9SLC6A5 | |
| SCHEMBL30006038 | 0.78 | HTT (0.63) | LMNAMAPTHTTMEN1KMT2A | |
| SCHEMBL23538890 | 0.77 | ALDH1A1 (0.68) | LMNAHTTSLC6A9SLC6A5KMT2A | |
| SCHEMBL5464512 | 0.77 | ADRB1 (0.54) | LMNASLC6A9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080060-A1 | SUBSTITUTED PIPERAZINE ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |