Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 6/20 | 0.46 |
| ▸ | NOS1 | P29475 | 5/20 | 0.46 |
| ▸ | NOS3 | P29474 | 4/20 | 0.46 |
| ▸ | ARG2 | P78540 | 4/20 | 0.44 |
| ▸ | ARG1 | P05089 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17381816 | 1.00 | GSR (0.48) | GSRNOS2NOS1NOS3ARG2 | |
| Edetol SCHEMBL9135245 | 0.89 | GSR (0.62) | GSRNOS2NOS1NOS3ARG2 | |
| SCHEMBL19303739 | 0.82 | GPR84 (0.50) | BLM | |
| SCHEMBL21012170 | 0.82 | BLM (0.48) | CYP1A2BLM | |
| SCHEMBL17371224 | 0.82 | BLM (0.48) | CYP1A2BLM | |
| SCHEMBL1851220 | 0.82 | NOS2 (0.53) | GSRNOS2NOS1NOS3ARG2 | |
| SCHEMBL17371226 | 0.82 | L3MBTL1 (0.33) | NOS2NOS1NOS3 | |
| SCHEMBL17368055 | 0.81 | GRIK1 (0.50) | GSRSLC1A2SLC1A1GRIK1GRIK2 | |
| SCHEMBL23815592 | 0.80 | GSR (0.53) | GSRNOS2NOS1NOS3ARG2 | |
| SCHEMBL23682813 | 0.80 | GSR (0.53) | GSRNOS2NOS1NOS3ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210369866-A1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | TRANSLATE BIO, INC. | 2021-12-02 | — | — | US | disclosed |
| US-10912844-B2 | Biodegradable lipids for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2021-02-09 | — | — | US | disclosed |
| US-20200222558-A1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | RANA THERAPEUTICS, INC. | 2020-07-16 | — | — | US | disclosed |
| US-10286082-B2 | Biodegradable lipids for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2019-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369866-A1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | LIPA, SLC67A1, SREBF1 | GSR 2433/4885NOS2 1588/4885NOS1 1462/4885 |
| US-10912844-B2 | Biodegradable lipids for delivery of nucleic acids | LIPA, SLC67A1, SREBF1 | GSR 2433/4885NOS2 1588/4885NOS1 1462/4885 |
| US-10286082-B2 | Biodegradable lipids for delivery of nucleic acids | LIPA, SLC67A1, SREBF1 | GSR 2433/4885NOS2 1588/4885NOS1 1462/4885 |
| US-20200222558-A1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | LIPA, SLC67A1, SREBF1 | GSR 2433/4885NOS2 1588/4885NOS1 1462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.