Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14604995 | 0.78 | NR4A1 (0.56) | NR4A1NR4A2NR4A3PTGS1NQO2 | |
| SCHEMBL14095463 | 0.76 | LOXL2 (0.45) | — | |
| SCHEMBL27528866 | 0.76 | LOXL2 (0.45) | — | |
| SCHEMBL14604997 | 0.75 | ALOX5 (0.44) | PTGS1PTGS2LMNAPOLB | |
| SCHEMBL21022334 | 0.74 | NR4A1 (0.42) | THRATHRBNR4A1NR4A2NR4A3 | |
| SCHEMBL15587040 | 0.74 | HDAC3 (0.44) | EPHX2NR1H4LMNAPOLB | |
| SCHEMBL13071971 | 0.73 | ESR1 (0.34) | THRATHRBEPHX2NR1H4LMNA | |
| SCHEMBL18103219 | 0.73 | KMT2A (0.59) | THRATHRBEPHX2NR1H4LMNA | |
| SCHEMBL18905389 | 0.73 | THRB (0.36) | THRATHRB | |
| SCHEMBL10446347 | 0.72 | ALDH1A1 (0.41) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |