Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 5/20 | 0.36 |
| ▸ | THRA | P10827 | 4/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | IAPP | P10997 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21020735 | 0.74 | THRA (0.34) | NR4A1NR4A2NR4A3THRBTHRA | |
| SCHEMBL18103219 | 0.73 | KMT2A (0.59) | THRBTHRAEPHX2NR1H4LMNA | |
| SCHEMBL18290661 | 0.71 | MAPT (0.48) | THRBTHRAEPHX2NR1H4LMNA | |
| SCHEMBL15559816 | 0.70 | ALDH1A1 (0.41) | THRBTHRAEPHX2NR1H4LMNA | |
| SCHEMBL22868058 | 0.69 | SRD5A2 (0.50) | THRBTHRAEPHX2NR1H4LMNA | |
| SCHEMBL26496043 | 0.69 | THRB (0.33) | THRBTHRAHSD17B3FAAHEPHX2 | |
| SCHEMBL1505324 | 0.68 | ALDH1A1 (0.59) | NR4A1NR4A2THRBPOLBL3MBTL1 | |
| SCHEMBL13267851 | 0.68 | THRA (0.55) | THRBTHRAKMT2AALDH1A1 | |
| SCHEMBL13267787 | 0.67 | THRA (0.56) | THRBTHRAKMT2AALDH1A1 | |
| SCHEMBL13071971 | 0.67 | ESR1 (0.34) | THRBTHRAEPHX2NR1H4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |