Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | POLQ | O75417 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21021746 | 0.90 | CES2 (0.33) | CASP1TSHRALDH1A1CYP3A4PDE10A | |
| SCHEMBL21022031 | 0.84 | HSD17B1 (0.38) | CASP1TSHRALDH1A1CYP3A4PDE10A | |
| SCHEMBL21020615 | 0.82 | TSHR (0.37) | CASP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL21020737 | 0.78 | MAOA (0.39) | CASP1TSHRALDH1A1 | |
| SCHEMBL21021797 | 0.78 | L3MBTL1 (0.34) | ALDH1A1CYP3A4TDP1MAPTPOLB | |
| SCHEMBL21021337 | 0.74 | MEN1 (0.43) | TSHRALDH1A1TP53ALOX15TDP1 | |
| SCHEMBL21021731 | 0.74 | SLC6A2 (0.35) | PDE10A | |
| SCHEMBL21022306 | 0.73 | HRH4 (0.35) | ALDH1A1MAPT | |
| SCHEMBL21022138 | 0.72 | NPC1 (0.42) | CASP1TSHRALDH1A1MAPT | |
| SCHEMBL21020630 | 0.72 | GAA (0.35) | GAAMAPTPKMAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |