Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.39 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.34 |
| ▸ | KCNQ4 | P56696 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.31 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21019705 | 0.85 | MAOA (0.34) | MAOAMAOBKCNQ2 | |
| SCHEMBL21020615 | 0.85 | TSHR (0.37) | TSHRCASP1ALDH1A1 | |
| SCHEMBL21021848 | 0.78 | CASP1 (0.36) | TSHRCASP1ALDH1A1 | |
| SCHEMBL18146787 | 0.73 | CYP3A4 (0.46) | KCNQ2CYP1A2CYP2C8CYP2B6KCNQ4 | |
| SCHEMBL20076652 | 0.70 | TSHR (0.31) | TSHR | |
| SCHEMBL21022031 | 0.69 | HSD17B1 (0.38) | TSHRCASP1ALDH1A1 | |
| SCHEMBL21022138 | 0.68 | NPC1 (0.42) | CYP1A2TSHRCASP1ALDH1A1 | |
| SCHEMBL21021746 | 0.68 | CES2 (0.33) | TSHRCASP1ALDH1A1 | |
| SCHEMBL21020937 | 0.67 | CYP3A4 (0.36) | TSHR | |
| SCHEMBL14964429 | 0.63 | ALDH1A1 (0.52) | TSHRCASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |