SCHEMBL21021872

SCHEMBL21021872

C=C(c1cc(C)ccc1F)N(C)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
RAB9A P51151 2/20 0.39
TP53 P04637 2/20 0.36
MAPT P10636 2/20 0.36
NPC1 O15118 1/20 0.36
TSHR P16473 1/20 0.36
CASP3 P42574 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
LMNA P02545 3/20 0.35
FAAH O00519 1/20 0.35
PHGDH O43175 1/20 0.35
MGLL Q99685 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
KAT6A Q92794 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21021797 0.83 L3MBTL1 (0.34) MEN1KMT2AMAPTLMNAFAAH
SCHEMBL18160220 0.81 POLB (0.51) MEN1KMT2ARAB9ATP53MAPT
SCHEMBL21021755 0.81 LMNA (0.38) MEN1KMT2ARAB9ATP53MAPT
SCHEMBL21517194 0.80 NFE2L2 (0.36) MEN1KMT2ATP53MAPTTSHR
SCHEMBL21021337 0.77 MEN1 (0.43) MEN1KMT2ARAB9ATP53MAPT
SCHEMBL21021110 0.73 PDK2 (0.37) MEN1KMT2ATSHRSMN1; SMN2POLB
SCHEMBL21020577 0.72 CSNK2A1 (0.46) MEN1KMT2ARAB9ATP53MAPT
SCHEMBL21022102 0.72 ALDH1A1 (0.34) MEN1KMT2ARAB9ATSHRSMN1; SMN2
SCHEMBL21021316 0.71 ALDH1A1 (0.36) MEN1KMT2ARAB9AMAPTTSHR
SCHEMBL21021746 0.71 CES2 (0.33) TP53MAPTTSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283459-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed