Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20076864 | 0.89 | AHR (0.61) | PTGS1ALOX5PTGS2TUBB1NFE2L2 | |
| SCHEMBL12603780 | 0.87 | PTGS1 (0.52) | PTGS1ALOX5PTGS2TUBB1NFE2L2 | |
| SCHEMBL21021188 | 0.85 | NFE2L2 (0.69) | PTGS1ALOX5PTGS2NFE2L2CHRNB2 | |
| SCHEMBL13790220 | 0.84 | PTGS1 (0.61) | PTGS1NFE2L2AHRNQO2 | |
| SCHEMBL5462179 | 0.82 | PTGS1 (0.51) | PTGS1NFE2L2AHRNQO2HIF1A | |
| SCHEMBL6465459 | 0.81 | AHR (0.68) | PTGS1NFE2L2AHRNQO2HIF1A | |
| SCHEMBL6459927 | 0.81 | AHR (0.68) | PTGS1NFE2L2AHRNQO2HIF1A | |
| SCHEMBL6803478 | 0.81 | AHR (0.68) | PTGS1NFE2L2AHRNQO2HIF1A | |
| SCHEMBL14363044 | 0.79 | NFE2L2 (0.71) | PTGS1ALOX5PTGS2TUBB1NFE2L2 | |
| SCHEMBL18163146 | 0.78 | ESR1 (0.59) | PTGS1PTGS2TUBB1AHRCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10815203-B2 | Analogs of fexaramine and methods of making and using | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2020-10-27 | — | — | US | disclosed |
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10815203-B2 | Analogs of fexaramine and methods of making and using | FXR2, FXR1, SLC10A2 | PTGS1 723/4885ALOX5 424/4885PTGS2 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.