SCHEMBL2102688

SCHEMBL2102688

CN[Si](Cl)(c1ccccc1)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.33
LMNA P02545 1/20 0.33
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.32
ATM Q13315 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2100791 0.79 KCNN4 (0.36) KCNN4LMNACYP2D6
SCHEMBL2101836 0.77 KCNN4 (0.39) KCNN4LMNACYP2D6TSHRATM
SCHEMBL2101131 0.73 KCNN4 (0.36) KCNN4LMNACYP2D6TSHRATM
SCHEMBL2273505 0.73 KCNN4 (0.36) KCNN4LMNACYP2D6TSHRATM
SCHEMBL4241 0.72 ESR1 (0.34) LMNATSHRATMESR1ESR2
SCHEMBL2102659 0.72 TSHR (0.38) KCNN4LMNATSHRATMESR1
SCHEMBL28069640 0.72 ESR1 (0.34) LMNATSHRATMESR1ESR2
SCHEMBL2100774 0.72 TSHR (0.38) KCNN4LMNATSHRATMESR1
SCHEMBL450654 0.72 TAAR1 (0.36) LMNACYP2D6TSHRATMESR1
SCHEMBL708403 0.72 ESR1 (0.34) LMNATSHRATMESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed