Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16259689 | 0.81 | HMGCR (0.42) | HMGCR | |
| SCHEMBL173244 | 0.73 | HMGCR (0.46) | HMGCR | |
| SCHEMBL13397821 | 0.73 | HMGCR (0.39) | HMGCRRORC | |
| SCHEMBL13812332 | 0.69 | HMGCR (0.49) | HMGCR | |
| SCHEMBL24848629 | 0.69 | CYP3A4 (0.59) | HMGCR | |
| SCHEMBL12257766 | 0.66 | KDM4E (0.39) | HMGCR | |
| SCHEMBL7255653 | 0.65 | HMGCR (0.37) | HMGCR | |
| SCHEMBL19051434 | 0.65 | HSD17B10 (0.42) | HMGCR | |
| SCHEMBL26020405 | 0.65 | HMGCR (0.37) | HMGCR | |
| SCHEMBL26022486 | 0.65 | HSP90AA1 (0.41) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | PHENEX PHARMACEUTICALS AG (DE) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | RORA, RORB, RORC | HMGCR 2596/4885RORC 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.