Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 2/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22995057 | 0.87 | CHRM2 (0.46) | SLC5A1SLC5A2CHRM2SIGMAR1L3MBTL1 | |
| SCHEMBL21029204 | 0.84 | LTA4H (0.46) | SLC5A1SLC5A2KMT2ASMN1; SMN2 | |
| SCHEMBL19034506 | 0.81 | SLC5A1 (0.61) | SLC5A1SLC5A2CHRM2KMT2AHPGD | |
| SCHEMBL20803450 | 0.77 | L3MBTL1 (0.65) | CHRM2KMT2ASIGMAR1L3MBTL1HPGD | |
| SCHEMBL21028739 | 0.77 | KMT2A (0.49) | SLC5A1SLC5A2KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL22995083 | 0.74 | L3MBTL1 (0.44) | SLC5A1CHRM2KMT2ASIGMAR1L3MBTL1 | |
| SCHEMBL20802902 | 0.73 | LTA4H (0.39) | CHRM2 | |
| SCHEMBL340998 | 0.73 | SIGMAR1 (0.48) | KMT2ASIGMAR1HPGDSMN1; SMN2 | |
| SCHEMBL19034462 | 0.72 | POLB (0.49) | SLC5A1SLC5A2KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL24029783 | 0.72 | SLC5A1 (0.46) | SLC5A1SLC5A2HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489226-A1 | INHIBITORS OF SODIUM GLUCOSE COTRANSPORTER 1 | Lexicon Pharmaceuticals, Inc. (US) | 2019-05-29 | — | — | EP | disclosed |