Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936240 | 0.81 | KMT2A (0.50) | MAPTGAARAB9ALMNAMEN1 | |
| SCHEMBL13036524 | 0.81 | SIGMAR1 (0.55) | SIGMAR1MAPTGAAATMTAAR1 | |
| SCHEMBL15387232 | 0.78 | SIGMAR1 (0.52) | SIGMAR1MAPTGAAATMTAAR1 | |
| SCHEMBL27870822 | 0.77 | MEN1 (0.42) | SIGMAR1MAPTATMTAAR1NPC1 | |
| SCHEMBL19971105 | 0.74 | SIGMAR1 (0.45) | SIGMAR1MAPTMEN1MAPK1KMT2A | |
| SCHEMBL340965 | 0.74 | LMNA (0.52) | TAAR1ALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL283735 | 0.73 | SIGMAR1 (0.81) | SIGMAR1MAPTGAAATMTAAR1 | |
| SCHEMBL549085 | 0.73 | SIGMAR1 (0.55) | SIGMAR1MAPTGAAATMTAAR1 | |
| SCHEMBL21028748 | 0.73 | SLC5A1 (0.43) | SIGMAR1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL96457 | 0.72 | TAAR1 (0.52) | MAPTATMTAAR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651876-B1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECH AG (CH) | 2017-08-09 | — | — | EP | claimed |
| US-8877955-B2 | Secondary aminosilanes | SIKA TECHNOLOGY AG (CH) | 2014-11-04 | — | — | US | claimed |
| US-20130281562-A1 | SECONDARY AMINOSILANES | SIKA TECHNOLOGY AG (CH) | 2013-10-24 | — | — | US | claimed |
| EP-2651876-A1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | Sika Technology AG (CH) | 2013-10-23 | — | — | EP | claimed |
| US-20130261270-A1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2013-10-03 | — | — | US | claimed |
| EP-2468759-A1 | Secondary Aminosilanes | Sika Technology AG (CH) | 2012-06-27 | — | — | EP | claimed |
| WO-2012080265-A1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2012-06-21 | — | — | WO | claimed |
| EP-2465843-A1 | Polyamines with secondary aliphatic amines | Sika Technology AG (CH) | 2012-06-20 | — | — | EP | claimed |
| EP-4626995-A1 | MOISTURE AND HEAT-CURABLE SEALING COMPOSITION | Sika Technology AG (CH) | 2025-10-08 | — | — | EP | disclosed |
| US-12209157-B2 | Polyurethane composition having a low content of monomeric diisocyantes | SIKA TECHNOLOGY AG (CH) | 2025-01-28 | — | — | US | disclosed |
| EP-3484898-B1 | METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2023-06-28 | — | — | EP | disclosed |
| CN-112533972-B | Polyurethane compositions with low levels of monomeric diisocyanates | SIKA技术股份公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-4053134-A1 | METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE | Momentive Performance Materials Inc. (US) | 2022-09-07 | — | — | EP | disclosed |
| CN-109563111-B | Method for stabilizing imino-functional silanes | 莫门蒂夫性能材料股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| EP-2236535-A1 | Humidity curing polyurethane composition being accelerated by influence of heat | Sika Technology AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| EP-2236533-A1 | Heat curing or heat activatable composition comprising a surface deactivated polyisocyanate | Sika Technology AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2010-04-29 | — | — | US | disclosed |
| EP-2178828-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE | Sika Technology AG (CH) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009010522-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE | SIKA TECHNOLOGY AG (CH) | 2009-01-22 | — | — | WO | disclosed |
| EP-2017260-A1 | Aldimines and compounds containing aldimine | Sika Technology AG (CH) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281562-A1 | SECONDARY AMINOSILANES | AS3MT, SRM, MSN | SIGMAR1 1574/4885MAPT 2333/4885GAA 1334/4885 |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | ALDH7A1, ILK, ALDH3A1 | SIGMAR1 4284/4885MAPT 456/4885GAA 873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.